ArticleFrontiers in neuroscience2020
Stability or Plasticity? - A Hierarchical Allostatic Regulation Model of Medial Prefrontal Cortex Function for Social Valuation.
Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- Neural Processes Linking Interoception to Moral Preferences Aligned with Group Consensus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Neural representations in MPFC and insula encode individual differences in estimating others' preferences.Social cognitive and affective neuroscience · 2025Article
- Altered neural response to social awkwardness in schizophrenia spectrum disorders.Social cognitive and affective neuroscience · 2024Article
- Self-interest overrides rank-reversal aversion in resource distribution.Scientific reports · 2024Article
- Transcranial direct current stimulation suggests a causal role of the medial prefrontal cortex in learning social hierarchy.Communications biology · 2024Article
- Individuals' contribution to household energy savings: The role of big-two personality traits.Heliyon · 2024Article
- Directed causal effect with PCMCI in hyperscanning EEG time series.Frontiers in neuroscience · 2024Article
- Distinctive Roles of Medial Prefrontal Cortex Subregions in Strategic Conformity to Social Hierarchy.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Brain connectivity during social exclusion differs depending on the closeness within a triad among older adults living in a village.Social cognitive and affective neuroscience · 2023Article
- Altered default mode network causal connectivity patterns in autism spectrum disorder revealed by Liang information flow analysis.Human brain mapping · 2023Article
- Can prosocial values improve brain health?Frontiers in neurology · 2023Article
- Distinctive roles of mPFC subregions in forming impressions and guiding social interaction based on others' social behaviour.Social cognitive and affective neuroscience · 2022Article
- Personal socio-cultural preferences modulate neural correlates of decisions to socialize with powerful persons.Human brain mapping · 2022Article
- Self-Enhancement and the Medial Prefrontal Cortex: The Convergence of Clinical and Experimental Findings.Brain sciences · 2022Review
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
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Abstract
The medial prefrontal cortex (mPFC) has long been recognized as the key component of the neurocircuitry involved in various social as well as non-social behaviors, however, little is known regarding the organizing principle of distinctive subregions in the mPFC that integrates a wide range of mPFC functions. The present study proposes a hierarchical model of mPFC functionality, where three functionally dissociable subregions, namely, the ventromedial prefrontal cortex (vmPFC), rostromedial prefrontal cortex (rmPFC), and dorsomedial prefrontal cortex (dmPFC), are differentially involved in computing values of decision-making. According to this model, the mPFC subregions interact with each other in such a way that more dorsal regions utilize additional external sensory information from environment to predict and prevent conflicts occurring in more ventral regions tuned to internal bodily signals, thereby exerting the hierarchically organized allostatic regulatory control over homeostatic reflexes. This model also emphasizes the role of the thalamic reticular nucleus (TRN) in arbitrating the transitions between different thalamo-cortical loops, detecting conflicts between competing options for decision-making, and in shifting flexibly between decision modes. The hierarchical architecture of the mPFC working in conjunction with the TRN may play a key role in adjusting the internal (bodily) needs to suit the constraints of external (environmental) variables better, thus effectively addressing the stability-plasticity dilemma.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.