Evidence map›Paper›PMID 32296254›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2019

Simultaneous extracellular and intracellular quantification of EGFR using paired-agent imaging in an

Kimberley S Samkoe, Emily Schultz, Allison Solanki, Lei Wang, Jesse Korber, Kenneth M Tichauer, Summer L Gibbs

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kimberley S SamkoeGeisel School of Medicine, Dartmouth College, Hanover, NH 03755.
Emily SchultzDepartment of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois, 60616.
Allison SolankiDepartment of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois, 60616.
Lei WangDepartment of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois, 60616.
Jesse KorberDepartment of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois, 60616.
Kenneth M TichauerDepartment of Biomedical Engineering, Oregon Health and Science University, Portland, OR, 97201.
Summer L GibbsDepartment of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois, 60616.
Illinois Institute of Technology · USDartmouth College · USOregon Health & Science University · US

Funding

Multi-probe fluorescence imaging for rapid intra-operative tumor margin assessmentR01CA188491 · NCI · DARTMOUTH COLLEGE · PI DAVIS, SCOTT C · 2015 to 2019
$2.9M
Paired-agent imaging for resection during surgery (PAIRS) for head & neck cancersR37CA212187 · NCI · DARTMOUTH-HITCHCOCK CLINIC · PI SAMKOE, KIMBERLEY · 2018 to 2024
$2.7M
NCI NIH HHS R01 CA188491NCI NIH HHS R37 CA212187
6 · The paper itself

Abstract

Quantification of protein concentrations is often a static and tissue destructive technique. Paired-agent imaging (PAI) using matched targeted and untargeted agents has been established as a dynamic method for quantifying the extracellular domain of epidermal growth factor receptor (EGFR)

Indexed as

chicken chorioallantoic membraneepidermal growth factor receptorintracellular paired agent imagingmulti-spectral imagingpaired-agent imaging

Identifiers

PMID32296254
PMCPMC7158268
OpenAlexW2920059231

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.