Evidence map›Paper›PMID 32296140›Full record

ReviewNature reviews. Gastroenterology & hepatology2020

Global burden of irritable bowel syndrome: trends, predictions and risk factors.

Christopher J Black, Alexander C Ford

2 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Gastroenterology & hepatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 317 papers, 18 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
317citing papers in PubMed, 18 pooled it
47.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06097598 unknown statusnot on this mapstarted 2023, after this paper: background citation

Prevalence of Irritable Bowel Syndrome in Medical Students in the Middle East and North Africa

TypeobservationalSponsorAssiut UniversityRan2023 to 2024Enrolled1,131ConditionsFaculty of Medicine
NCT06676488 nacompletednot on this mapstarted 2025, after this paper: background citation

A Randomized Crossover Trial of Bright Light Therapy in Irritable Bowel Syndrome

TypeinterventionalSponsorMedical University of South CarolinaRan2025 to 2026Enrolled5ConditionsIrritable Bowel Syndrome (IBS), Circadian MisalignmentArmsRe-Timer glasses, Placebo Device
3 · Its place in the literature

Who cites it

317 citing papers in PubMed, 18 syntheses or guidelines pooled it, 578 citations in OpenAlex.

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257 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Christopher J BlackLeeds Gastroenterology Institute, St. James's University Hospital, Leeds, UK.ORCID http://orcid.org/0000-0001-5449-3603
Alexander C FordLeeds Gastroenterology Institute, St. James's University Hospital, Leeds, UK. alexf12399@yahoo.com.
University of Leeds · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Irritable bowel syndrome (IBS) is one of the most common disorders of gut-brain interaction worldwide, defined according to patterns of gastrointestinal symptoms as described by the Rome diagnostic criteria. However, these criteria, developed with reference to research conducted largely in Western populations, might be limited in their applicability to other countries and cultures. Epidemiological data show a wide variation in the prevalence of IBS globally and more rigorous studies are needed to accurately determine any differences that might exist between countries as well as the potential explanations. The effects of IBS on the individual, in terms of their quality of life, and on health-care delivery and society, in terms of economic costs, are considerable. Although the magnitude of these effects seems to be comparable between nations, their precise nature can vary based on the existence of societal and cultural differences. The pathophysiology of IBS is complex and incompletely understood; genetics, diet and the gut microbiome are all recognized risk factors, but the part they play might be influenced by geography and culture, and hence their relative importance might vary between countries. This Review aims to provide an overview of the burden of IBS in a global context, to discuss future implications for the care of people with IBS worldwide, and to identify key areas for further research.

Indexed as

AbsenteeismCost of IllnessHealth Care CostsQuality of LifeAutonomic Nervous SystemDietDysbiosisGastrointestinal MicrobiomeGenetic Predisposition to DiseaseGlobal HealthHumansHypothalamo-Hypophyseal SystemIntestinal MucosaIrritable Bowel SyndromePermeabilityPrevalence

Identifiers

PMID32296140
OpenAlexW3016802365

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.