ArticleNature communications2020
A gravity-based three-dimensional compass in the mouse brain.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 65 citations in OpenAlex.
- Hippocampal place cells map terrain geometry independently of behavior.Science advances · 2026Article
- Head direction cells use a head-referenced dual-axis updating rule in 3D space.Communications biology · 2026Article
- Simultaneous path-integration recalibration in head direction and place cells.Current biology : CB · 2026Article
- Multisensory coding of self-motion and its contribution to navigation.Nature reviews. Neuroscience · 2025Review
- Synchronized path-integration recalibration but distinct landmark-control dynamics in head direction and CA1 place cells.bioRxiv : the preprint server for biology · 2025Article
- DISSeCT: An unsupervised framework for high-resolution mapping of rodent behavior using inertial sensors.PLoS biology · 2025Article
- Evolutionarily conserved brainstem architecture enables gravity-guided vertical navigation.PLoS biology · 2024Article
- Modeling hippocampal spatial cells in rodents navigating in 3D environments.Scientific reports · 2024Article
- A brainstem circuit for gravity-guided vertical navigation.bioRxiv : the preprint server for biology · 2024Article
- Interactions between rodent visual and spatial systems during navigation.Nature reviews. Neuroscience · 2023Review
- Computational cross-species views of the hippocampal formation.Hippocampus · 2023Review
- Review
- Temporal and spatial properties of vestibular signals for perception of self-motion.Frontiers in neurology · 2023Review
- Article
- Automatic mapping of multiplexed social receptive fields by deep learning and GPU-accelerated 3D videography.Nature communications · 2022Article
- Mapping vestibular and visual contributions to angular head velocity tuning in the cortex.Cell reports · 2021Article
- Article
- Impact of gravity on the perception of linear motion.Journal of neurophysiology · 2021Article
- Body language signals for rodent social communication.Current opinion in neurobiology · 2021Review
- Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Gravity sensing provides a robust verticality signal for three-dimensional navigation. Head direction cells in the mammalian limbic system implement an allocentric neuronal compass. Here we show that head-direction cells in the rodent thalamus, retrosplenial cortex and cingulum fiber bundle are tuned to conjunctive combinations of azimuth and tilt, i.e. pitch or roll. Pitch and roll orientation tuning is anchored to gravity and independent of visual landmarks. When the head tilts, azimuth tuning is affixed to the head-horizontal plane, but also uses gravity to remain anchored to the allocentric bearings in the earth-horizontal plane. Collectively, these results demonstrate that a three-dimensional, gravity-based, neural compass is likely a ubiquitous property of mammalian species, including ground-dwelling animals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.