Evidence map›Paper›PMID 32295877›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

The type IV pilin PilA couples surface attachment and cell-cycle initiation in

Luca Del Medico, Dario Cerletti, Philipp Schächle, Matthias Christen, Beat Christen

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Electron Cryo-Tomography Reveals thebioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Plants (Basel, Switzerland) · 2024
    Article
  11. Article
  12. Article
  13. Tad and toxin-coregulated pilus structures reveal unexpected diversity in bacterial type IV pili.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  14. Article
  15. Article
  16. Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  17. Review
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  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Luca Del MedicoInstitute of Molecular Systems Biology, Department of Biology, Eidgenössische Technische HochschuleZürich, Zürich 8093, Switzerland.
Dario CerlettiInstitute of Molecular Systems Biology, Department of Biology, Eidgenössische Technische HochschuleZürich, Zürich 8093, Switzerland.
Philipp SchächleInstitute of Molecular Systems Biology, Department of Biology, Eidgenössische Technische HochschuleZürich, Zürich 8093, Switzerland.ORCID 0000-0002-6343-2957
Matthias ChristenInstitute of Molecular Systems Biology, Department of Biology, Eidgenössische Technische HochschuleZürich, Zürich 8093, Switzerland beat.christen@imsb.biol.ethz.ch matthias.christen@imsb.biol.ethz.ch.ORCID 0000-0001-7724-4562
Beat ChristenInstitute of Molecular Systems Biology, Department of Biology, Eidgenössische Technische HochschuleZürich, Zürich 8093, Switzerland beat.christen@imsb.biol.ethz.ch matthias.christen@imsb.biol.ethz.ch.ORCID 0000-0002-9528-3685
ETH Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding how bacteria colonize surfaces and regulate cell-cycle progression in response to cellular adhesion is of fundamental importance. Here, we use transposon sequencing in conjunction with fluorescence resonance energy transfer (FRET) microscopy to uncover the molecular mechanism for how surface sensing drives cell-cycle initiation in

Indexed as

Bacterial AdhesionCaulobacter crescentusCell CycleFimbriae ProteinsGene Expression Regulation, BacterialFimbriae ProteinsCaulobacter crescentusc-di-GMPFRET microscopyTnSeqtype IV pilin

Identifiers

PMID32295877
PMCPMC7196804
OpenAlexW3016433524

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.