Evidence map›Paper›PMID 32295771›Full record

ArticleeNeuro

Propofol Modulates Early Memory Consolidation in Humans.

Daa Un Moon, Nazli Esfahani-Bayerl, Carsten Finke, Daniel J Salchow, Mario Menk, Simon Bayerl, Richard Kempter, Christoph J Ploner

Abstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daa Un MoonDepartment of Neurology, Charité - Universitätsmedizin Berlin, Berlin D-13353, Germany.
Nazli Esfahani-BayerlDepartment of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Berlin D-10117, Germany.
Carsten FinkeDepartment of Neurology, Charité - Universitätsmedizin Berlin, Berlin D-13353, Germany.ORCID 0000-0002-7665-1171
Daniel J SalchowDepartment of Ophthalmology, Charité - Universitätsmedizin Berlin, Berlin D-13353, Germany.
Mario MenkDepartment of Anesthesiology, Charité - Universitätsmedizin Berlin, Berlin D-13353, Germany.
Simon BayerlDepartment of Neurosurgery, Charité - Universitätsmedizin Berlin, Berlin D-10117, Germany.
Richard KempterInstitute for Theoretical Biology, Department of Biology, Humboldt-Universität zu Berlin, Berlin D-10115, Germany.ORCID 0000-0002-5344-2983
Christoph J PlonerDepartment of Neurology, Charité - Universitätsmedizin Berlin, Berlin D-13353, Germany christoph.ploner@charite.de.ORCID 0000-0003-0983-4530

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maintenance of memory across time is crucial for adaptive behavior. Current theories posit that the underlying consolidation process depends on stabilization of synapses and reorganization of interactions between hippocampus and neocortex. However, the temporal properties of hippocampal-neocortical network reconfiguration during consolidation are still a matter of debate. Translational research on this issue is challenged by the paucity of techniques to transiently interfere with memory in the healthy human brain. Here, we report a neuro-pharmacological approach with the GABA

Indexed as

Memory ConsolidationPropofolHippocampusHumansMemoryMental RecallPropofolgeneral anesthesiahippocampusmemory consolidationpropofolsynaptic consolidationsystems consolidation

Identifiers

PMID32295771
PMCPMC7307630

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.