Evidence map›Paper›PMID 32295085›Full record

ArticleMicromachines2020

A Microfluidic-Based Investigation of Bacterial Attachment in Ureteral Stents.

Antonio De Grazia, Gareth LuTheryn, Alireza Meghdadi, Ali Mosayyebi, Erika J Espinosa-Ortiz, Robin Gerlach, Dario Carugo

Open access · goldAbstract read
In one paragraph

Article in Micromachines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
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  5. Ultrasound-activated cilia for biofilm control in indwelling medical devices.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  12. Computational simulation of the flow dynamic field in a porous ureteric stent.Medical & biological engineering & computing · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Antonio De GraziaBioengineering Science Research Group, Faculty of Engineering and Physical Sciences, University of Southampton, Southampton SO17 1BJ, UK.
Gareth LuTherynBioengineering Science Research Group, Faculty of Engineering and Physical Sciences, University of Southampton, Southampton SO17 1BJ, UK.
Alireza MeghdadiBioengineering Science Research Group, Faculty of Engineering and Physical Sciences, University of Southampton, Southampton SO17 1BJ, UK.
Ali MosayyebiBioengineering Science Research Group, Faculty of Engineering and Physical Sciences, University of Southampton, Southampton SO17 1BJ, UK.
Erika J Espinosa-OrtizCenter for Biofilm Engineering and Department of Chemical and Biological Engineering, Montana State University, Bozeman, MT 59717, USA.
Robin GerlachCenter for Biofilm Engineering and Department of Chemical and Biological Engineering, Montana State University, Bozeman, MT 59717, USA.
Dario CarugoBioengineering Science Research Group, Faculty of Engineering and Physical Sciences, University of Southampton, Southampton SO17 1BJ, UK.
University of Southampton · GBMontana State University · US

Funding

Biotechnology and Biological Sciences Research Council BB/R012415/1
6 · The paper itself

Abstract

Obstructions of the ureter lumen can originate from intrinsic or extrinsic factors, such as kidney stones, tumours, or strictures. These can affect the physiological flow of urine from the kidneys to the bladder, potentially causing infection, pain, and kidney failure. To overcome these complications, ureteral stents are often deployed clinically in order to temporarily re-establish urinary flow. Despite their clinical benefits, stents are prone to encrustation and biofilm formation that lead to reduced quality of life for patients; however, the mechanisms underlying the formation of crystalline biofilms in stents are not yet fully understood. In this study, we developed microfluidic-based devices replicating the urodynamic field within different configurations of an occluded and stented ureter. We employed computational fluid dynamic simulations to characterise the flow dynamic field within these models and investigated bacterial attachment (

Indexed as

bacterial attachmentbiofilm formationcavity flowCFD simulationsmicrofluidicsstent-on-a-chipureteral obstructionureteral stentwall shear stress

Identifiers

PMID32295085
PMCPMC7231375
OpenAlexW3016017778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.