Evidence map›Paper›PMID 32294984›Full record

ArticleMolecules (Basel, Switzerland)2020

Effects of Length and Loop Composition on Structural Diversity and Similarity of (G

Jie Li, I-Te Chu, Ting-An Yeh, De-Yu Chen, Chiung-Lin Wang, Ta-Chau Chang

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jie LiInstitute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan.
I-Te ChuInstitute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan.
Ting-An YehInstitute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan.
De-Yu ChenInstitute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan.
Chiung-Lin WangInstitute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan.
Ta-Chau ChangInstitute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan.ORCID 0000-0001-5878-8556

Funding

Academia Sinica AS-102-TPA07Ministry of Science and Technology MOST-106-2119-M-001-030-MY3
6 · The paper itself

Abstract

A G-rich sequence containing three loops to connect four G-tracts with each ≥2 guanines can possibly form G-quadruplex structures. Given that all G-quadruplex structures comprise the stacking of G-quartets, the loop sequence plays a major role on their folding topology and thermal stability. Here circular dichroism, NMR, and PAGE are used to study the effect of loop length and base composition in the middle loop, and a single base difference in loop 1 and 3 on G-quadruplex formation of (G

Indexed as

Models, MolecularBase SequenceCircular DichroismDNAElectrophoresis, Polyacrylamide GelG-QuadruplexesLigandsMagnetic Resonance SpectroscopyNucleic Acid ConformationNucleotidesPotassiumDNALigandsNucleotidesPotassiumbase compositionflanking nucleotideG-quadruplexloop lengthquadruplex-duplex junctionstructural diversitystructural similarity

Identifiers

PMID32294984
PMCPMC7221631

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.