Development and Validation of Liquid Chromatography-Tandem Mass Spectrometry Method for Pharmacokinetic Evaluation of 7β-(3-Ethyl-cis-crotonoyloxy)-1α-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranon in Rats.
Nae-Won Kang, Jae-Young Lee, Kwangho Song, Min-Hwan Kim, Soyeon Yoon, Duy-Thuc Nguyen, Sungho Kim, Yeong Shik Kim, Dae-Duk Kim
Open access · goldAbstract readEvaluation StudyValidation Study
Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 2 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
9 authors at 2 institutions in 1 country.
Nae-Won KangCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Korea.
Jae-Young LeeCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Kwangho SongNatural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 08826, Korea.
Min-Hwan KimCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Korea.
Soyeon YoonCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Korea.
Duy-Thuc NguyenCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Korea.
Sungho KimCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Korea.
Yeong Shik KimNatural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 08826, Korea.
Dae-Duk KimCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Korea.ORCID 0000-0003-0093-3874
Seoul National University · KRChungnam National University · KR
Funding
National Research Foundation of Korea NRF-2017R1E1A1A01074584National Research Foundation of Korea NRF-2018M3A7B4071203
6 · The paper itself
Abstract
Recently, potent neuroprotective and anti-diabetic effects of 7
Indexed as
AcetonitrilesAdministration, OralAnimalsCalibrationChromatography, High Pressure LiquidFormatesLimit of DetectionLosartanMalePharmacokineticsPlant ExtractsQuality ControlRatsRats, Sprague-DawleySesquiterpenesTandem Mass SpectrometryacetonitrileAcetonitrilesFormatesformic acidLosartanPlant ExtractsSesquiterpenes7β-(3-Ethyl-cis-crotonoyloxy)-1α-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranoneKeywords: ECNLC-MS/MSPharmacokineticsTussilago farfara LinnaeusValidation
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Development and Validation of Liquid Chromatography-Tandem Mass Spectrometry Method for Pharmacokinetic Evaluation of 7β-(3-Ethyl-cis-crotonoyloxy)-1α-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranon in Rats. · full record | OpenQuestion