Evidence map›Paper›PMID 32294900›Full record

ArticleMarine drugs2020

Cytotoxic Activity of Aplykurodin A Isolated From

Jaehoo Lee, Wei Zhou, MinKyun Na, Sangtaek Oh

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Jaehoo LeeDepartment of Bio and Fermentation Convergence Technology, BK21 PLUS Program, Kookmin University, Seoul 136-702, Korea.
Wei ZhouCollege of Pharmacy, Yanbian University, Yanji 133002, China.
MinKyun NaCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Sangtaek OhDepartment of Bio and Fermentation Convergence Technology, BK21 PLUS Program, Kookmin University, Seoul 136-702, Korea.
Kookmin University · KRChungnam National University · KRYanbian University · CN

Funding

National Research Foundation of Korea NRF-2018R1D1A1B07048208
6 · The paper itself

Abstract

Dysregulation of the Wnt/β-catenin signaling pathway is involved in the development of human hepatocellular carcinoma and has thus emerged as a therapeutic target for this malignant tumor. In this study, we employed sensitive cell-based assays to identify aplykurodin A isolated from

Indexed as

AplysiaAnimalsAntineoplastic Agentsbeta CateninCell Line, TumorGene Expression Regulation, NeoplasticHumansIndansLactonesWnt Signaling PathwayAntineoplastic Agentsaplykurodinone-1beta CateninIndansLactonesaplykurodin Aapoptosisautophagyhepatocellular carcinoma (HCC)Wnt/β-catenin signaling

Identifiers

PMID32294900
PMCPMC7230895
OpenAlexW3016160106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.