Evidence map›Paper›PMID 32294671›Full record

ArticleClinics (Sao Paulo, Brazil)2020

Real-world evidence of health outcomes and medication use 24 months after bariatric surgery in the public healthcare system in Brazil: a retrospective, single-center study.

Denis Pajecki, Flavio Kawamoto, Anna Carolina Batista Dantas, Priscila Caldeira Andrade, Nissia Capello Brasil, Silvio Mauro Junqueira, Fernanda Maria Pirozelli de Oliveira, Rodrigo Antonini Ribeiro, Marco Aurelio Santo

Open access · goldAbstract read
In one paragraph

Article in Clinics (Sao Paulo, Brazil), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Denis PajeckiDivisao de Cirurgia, Unidade de Cirurgia Bariatrica e Metabolica, Departamento de Gastroenterologia, Hospital das Clinicas (HCFMUSP), Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.ORCID 0000-0002-0898-9285
Flavio KawamotoDivisao de Cirurgia, Unidade de Cirurgia Bariatrica e Metabolica, Departamento de Gastroenterologia, Hospital das Clinicas (HCFMUSP), Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.
Anna Carolina Batista DantasDivisao de Cirurgia, Unidade de Cirurgia Bariatrica e Metabolica, Departamento de Gastroenterologia, Hospital das Clinicas (HCFMUSP), Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.ORCID 0000-0001-9505-6784
Priscila Caldeira AndradeJohnson & Johnson Medical Devices, Sao Paulo, SP, BR.ORCID 0000-0002-5707-0910
Nissia Capello BrasilJohnson & Johnson Medical Devices, Sao Paulo, SP, BR.
Silvio Mauro JunqueiraJohnson & Johnson Medical Devices, Sao Paulo, SP, BR.ORCID 0000-0002-7584-7260
Fernanda Maria Pirozelli de OliveiraJohnson & Johnson Medical Devices, Sao Paulo, SP, BR.ORCID 0000-0002-3513-2623
Rodrigo Antonini RibeiroHTAnalyze Consulting, Porto Alegre, RS, BR.ORCID 0000-0003-3080-3704
Marco Aurelio SantoDivisao de Cirurgia, Unidade de Cirurgia Bariatrica e Metabolica, Departamento de Gastroenterologia, Hospital das Clinicas (HCFMUSP), Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.ORCID 0000-0002-7813-6210
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRJohnson & Johnson (Brazil) · BRABS Consulting (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe number of bariatric procedures has significantly increased in Brazil, especially in the public Unified Health System. The present study describes health outcomes and medication use in obese patients treated in a major hospital that performs publicly funded surgery in Brazil.

methodsA retrospective, single center study was conducted to collect real-world evidence of health outcomes and medication use in 247 obese patients (female, 82.2%) who underwent open Roux-en-Y gastric bypass. Changes in weight and body mass index (BMI), presence of apnea, hypertension, and type 2 diabetes (T2D), and medication use (hypertension, diabetes, and dyslipidemia) were assessed preoperatively and up to 24 months postoperatively. The mean cost of medications was calculated for the 12-month preoperative and 24-month postoperative periods.

resultsDuring the surgery, the mean age of patients was 43.42 years (standard deviation [SD], 10.9 years), and mean BMI was 46.7 kg/m2 (SD, 6.7 kg/m2). At 24 months, significant declines were noted in weight (mean, -37.6 kg), BMI (mean, -14.3 kg/m2); presence of T2D, hypertension, and apnea (-29.6%, -50.6%, and -20.9%, respectively); and number of patients using medications (-66.67% for diabetes, -41.86% for hypertension, and -55.26% for dyslipidemia). The mean cost of medications (total costs for all medications) decreased by >50% in 12-24 postoperative months compared to that in 12 preoperative months.

conclusionRoux-en-Y gastric bypass successfully reduced weight, BMI, and comorbidities and medication use and cost at 24 months in Brazilian patients treated in the public Unified Health System.

Indexed as

Bariatric SurgeryLaparoscopyAdultBody Mass IndexBrazilDiabetes ComplicationsDiabetes Mellitus, Type 2Drug PrescriptionsDyslipidemiasFemaleGastric BypassGastroesophageal RefluxHumansHypertensionObesity, MorbidOutcome Assessment, Health Care

Identifiers

PMID32294671
PMCPMC7134550
OpenAlexW3015256809

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.