ArticleCell reports2020
Mouse Thermoregulation: Introducing the Concept of the Thermoneutral Point.
Article in Cell reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
110 citing papers in PubMed, 4 syntheses or guidelines pooled it, 166 citations in OpenAlex.
- Under Control? Mouse Models of Heat Exposure: A Systematic Review of Experimental Design and Methodology.Acta physiologica (Oxford, England) · 2026Pooled it
- The effects of heat stress on the ovary, follicles, and oocytes: a systematic review†.Biology of reproduction · 2025Pooled it
- Gut Microbial Community and Host Thermoregulation in Small Mammals.Frontiers in physiology · 2022Pooled it
- A Handful of Details to Ensure the Experimental Reproducibility on the FORCED Running Wheel in Rodents: A Systematic Review.Frontiers in endocrinology · 2021Pooled it
- Natural microbiota confer life-long protection against obesity via an early-life, immune-mediated effect on brown adipocytes.Gut microbes · 2026Article
- ACE2 downregulation contributes to adverse cardiovascular and reproductive outcomes in female mice on high-fat diet.American journal of physiology. Heart and circulatory physiology · 2026Article
- Limb restraint induces a rapid and profound decrease in core body temperature associated with the stress response in mice.PNAS nexus · 2026Article
- Using thermal preference to understand mouse thermal biology.American journal of physiology. Endocrinology and metabolism · 2026Article
- Housing Mice in Thermoneutrality Causes Tissue-specific Changes in Number, Identity, and Phase of Circadian-expressed mRNA Transcripts.bioRxiv : the preprint server for biology · 2026Article
- Article
- Hepatic ketogenesis is not required for exercise training to mitigate diet-induced liver steatosis in male mice.Function (Oxford, England) · 2026Article
- Subthreshold Thermal Stress Aggravates Methamphetamine-Induced Cardiomyocyte Pyroptosis via the Mitochondrial ROS/BAX/mtDNA/NLRP3 Pathway.International journal of molecular sciences · 2026Article
- Sexual dimorphism and photoperiodism in cognitive and neuronal ionic changes in scopolamine-induced cognitive impairment.Metabolic brain disease · 2026Article
- Intermittent exposure to high ambient heat during the second half of gestation in mice causes mild alterations of reproductive endpoints in male embryos.bioRxiv : the preprint server for biology · 2026Article
- Ambient temperature regulates CD4iScience · 2026Article
- Comparative analysis of naked mole-rat thermogenesis and its potential to maintain euthermia in response to cold.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- The effects of housing temperature on mouse physiology and implications for disease modeling.Lab animal · 2026Review
- Short-term time-restricted feeding improves metabolic rhythms and liver mitochondrial bioenergetic function in high-fat diet-fed mice.Function (Oxford, England) · 2026Article
- The poikilothermic hypothesis of sepsis.Critical care (London, England) · 2026Review
- Thermoregulatory adaptations to cold in C3H/HeJ mice are independent of ADRB3 signaling.Scientific reports · 2026Article
50 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Human and mouse thermal physiology differ due to dissimilar body sizes. Unexpectedly, in mice we found no ambient temperature zone where both metabolic rate and body temperature were constant. Body temperature began increasing once cold-induced thermogenesis was no longer required. This result reproduced in male, female, C57BL/6J, 129, chow-fed, diet-induced obese, and ob/ob mice as well as Trpv1
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.