Evidence map›Paper›PMID 32294125›Full record

ArticlePloS one2020

Multiple criteria decision analysis approach to consider therapeutic innovations in the emergency department: The methoxyflurane organizational impact in acute trauma pain.

Virginie Eve Lvovschi, Maxime Maignan, Karim Tazarourte, Mohamed Lamine Diallo, Caroline Hadjadj-Baillot, Nathalie Pons-Kerjean, Frederic Lapostolle, Claude Dussart

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Virginie Eve LvovschiEmergency Department, Rouen University Hospital, Normandie Univ, UNIROUEN, INSERM U1073, Rouen, France.ORCID 0000-0003-2903-1911
Maxime MaignanEmergency Department, Grenoble University Hospital, Univ. Grenoble Alpes, INSERM U1042, CHU Grenoble Alpes, HP2, Grenoble Alps University, Grenoble, France.
Karim TazarourteEmergency Department, Edouard Herriot Hospital, Lyon Public Hospices, Lyon, France; Health Services and Performance Research, HESPER, EA, Claude Bernard University, Lyon, France.
Mohamed Lamine DialloPharmacy Department, Grand Hôpital de l'Est Francilien, Meaux, France.
Caroline Hadjadj-BaillotPharmacy Department, CHU de Bordeaux, Bordeaux, France.
Nathalie Pons-KerjeanPharmacy Department, Beaujon Hospital, APHP, Clichy, France.
Frederic LapostolleSAMU 93, Avicenne Hospital-APHP, Bobigny, France; INSERM U942, Paris 13 University, Paris, France.
Claude DussartLyon Public Hospices, Central Pharmacy, Lyon, France; EA, Systemic Health Pathway Laboratory, University Claude Bernard, Lyon, France.
Inserm · FRUniversité Claude Bernard Lyon 1 · FRCentre Hospitalier Universitaire de Bordeaux · FRHôpital Beaujon · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute trauma pain is poorly managed in the emergency department (ED). The reasons are partly organizational: ED crowding and rare trauma care pathways contribute to oligoanalgesia. Anticipating the organizational impact of an innovative care procedure might facilitate the decision-making process and help to optimize pain management.

methodsWe used a multiple criteria decision analysis (MCDA) approach to consider the organizational impact of methoxyflurane (self-administered) in the ED, introduced alone or supported by a trauma care pathway. A MCDA experiment was designed for this specific context, 8 experts in emergency trauma care pathways (leading physicians and pharmacists working in French urban tertiary hospitals) were recruited. The study involved four steps: (i) Selection of organizational criteria for evaluating the innovation's impact; (ii) assessment of the relative weight of each criterion; (iii) choice of appropriate scenarios for exploring the organizational impact of MEOX under various contexts; and (iv) software-assisted simulation based on pairwise comparisons of the scenarios. The final outcome measure was the expected overall organizational impact of methoxyflurane on a 0-to-100 scale (score >50: positive impact).

resultsNine organizational criteria were selected. "Mean length of stay in the ED" was the most weighted. Methoxyflurane alone obtained 59 as a total score, with a putative positive impact for eight criteria, and a neutral effect on one. When a trauma care pathway was introduced concomitantly, the impact of methoxyflurane was greater overall (score: 75) and for each individual criterion.

conclusionsOur model highlighted the putative positive organizational impact of methoxyflurane in the ED-particularly when supported by a trauma care pathway-and the relevance of expert consensus in this particular pharmacoeconomic context. The MCDA approach could be extended to other research fields and healthcare challenges in emergency medicine.

Indexed as

Decision Support TechniquesAcute PainAnesthetics, InhalationClinical Decision-MakingCritical PathwaysCrowdingEmergency Service, HospitalEmergency TreatmentFranceHumansLength of StayMethoxyfluraneModels, OrganizationalOutcome and Process Assessment, Health CarePain ManagementPain MeasurementAnesthetics, InhalationMethoxyflurane

Identifiers

PMID32294125
PMCPMC7159203
OpenAlexW3015499307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.