ArticlePLoS genetics2020
An integrated analysis of cell-type specific gene expression reveals genes regulated by REVOLUTA and KANADI1 in the Arabidopsis shoot apical meristem.
Article in PLoS genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Dexamethasone-inducible LhGR/pOp system: simple and flexible spatiotemporal control of gene expression.Planta · 2026Review
- Cross-Species Reprogramming of Developmental Plasticity and Metabolic Rewiring via Banana-Derived WUS2 Developmental Regulator.Plant biotechnology journal · 2026Article
- TMO5 regulates PIN1 polarity convergence and organogenesis downstream of MONOPTEROS in the Arabidopsis shoot.Development (Cambridge, England) · 2025Article
- Genome-Wide Identification of theInternational journal of molecular sciences · 2025Article
- Genome-Wide Identification and Comprehensive Analysis of the GARP Transcription Factor Superfamily inGenes · 2025Article
- Genome-wide identification of the GLK transcription factor family in melon and its expression analysis under biotic and abiotic stresses.Frontiers in plant science · 2025Article
- The Ins and Outs of Homeodomain-Leucine Zipper/Hormone Networks in the Regulation of Plant Development.International journal of molecular sciences · 2024Review
- Global gene regulatory network underlying miR165a in Arabidopsis shoot apical meristem.Scientific reports · 2023Article
- Genetic robustness control of auxin output in priming organ initiation.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Unique and overlapping functions for the transcriptional regulatorsPlant direct · 2023Article
- Flower Development in Arabidopsis.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Protoplasting and Fluorescence-Activated Cell Sorting of the Shoot Apical Meristem Cell Types.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Identification and expression analysis of GARP superfamily genes in response to nitrogen and phosphorus stress in Spirodela polyrhiza.BMC plant biology · 2022Article
- Coactivation of antagonistic genes stabilizes polarity patterning during shoot organogenesis.Science advances · 2022Article
- KANADI promotes thallus differentiation and FR-induced gametangiophore formation in the liverwort Marchantia.The New phytologist · 2022Article
- Genome-Wide Identification and Characterization ofFrontiers in plant science · 2022Article
- Identification of GOLDEN2-like transcription factor genes in soybeans and their role in regulating plant development and metal ion stresses.Frontiers in plant science · 2022Article
- Integration of Core Mechanisms Underlying Plant Aerial Architecture.Frontiers in plant science · 2021Review
- Patterning a Leaf by Establishing Polarities.Frontiers in plant science · 2020Review
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Authors and funding
7 authors.
Funding
Abstract
In the Arabidopsis thaliana shoot apical meristem (SAM) the expression domains of Class III Homeodomain Leucine Zipper (HD-ZIPIII) and KANADI (KAN) genes are separated by a narrow boundary region from which new organs are initiated. Disruption of this boundary through either loss of function or ectopic expression of HD-ZIPIII and KAN causes ectopic or suppression of organ formation respectively, raising the question of how these transcription factors regulate organogenesis at a molecular level. In this study we develop a multi-channel FACS/RNA-seq approach to characterize global patterns of gene expression across the HD-ZIPIII-KAN1 SAM boundary. We then combine FACS, RNA-seq and perturbations of HD-ZIPIII and KAN expression to identify genes that are both responsive to REV and KAN1 and normally expressed in patterns that correlate with REV and KAN1. Our data reveal that a significant number of genes responsive to REV are regulated in opposite ways depending on time after induction, with genes associated with auxin response and synthesis upregulated initially, but later repressed. We also characterize the cell type specific expression patterns of auxin responsive genes and identify a set of genes involved in organogenesis repressed by both REV and KAN1.
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