Evidence map›Paper›PMID 32293767›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2020

Fluorescent Arylphosphonic Acids: Synergic Interactions between Bone and the Fluorescent Core.

Yunus Zorlu, Connor Brown, Claudia Keil, M Menaf Ayhan, Hajo Haase, Richard B Thompson, Imre Lengyel, Gündoğ Yücesan

Open access · hybridAbstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. A 2,7-dichlorofluorescein derivative to monitor microcalcifications.Molecular systems design & engineering · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Yunus ZorluDepartment of Chemistry, Faculty of Science, Gebze Technical University, 41400, Gebze-Kocaeli, Turkey.
Connor BrownWellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, BT9 7BL, UK.
Claudia KeilTechnische Universität Berlin, Chair of Food Chemistry and Toxicology, Straße des 17. Juni 135, 10623, Berlin, Germany.
M Menaf AyhanDepartment of Chemistry, Faculty of Science, Gebze Technical University, 41400, Gebze-Kocaeli, Turkey.
Hajo HaaseTechnische Universität Berlin, Chair of Food Chemistry and Toxicology, Straße des 17. Juni 135, 10623, Berlin, Germany.ORCID http://orcid.org/0000-0002-1622-8718
Richard B ThompsonDepartment of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, 21201, USA.
Imre LengyelWellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Belfast, BT9 7BL, UK.
Gündoğ YücesanTechnische Universität Berlin, Chair of Food Chemistry and Toxicology, Straße des 17. Juni 135, 10623, Berlin, Germany.ORCID http://orcid.org/0000-0002-5105-7280
Technische Universität Berlin · DEGebze Technical University · TRQueen's University Belfast · GBUniversity of Maryland, Baltimore · US

Funding

Imaging of Retinal Hydroxyapatite as an Early Screen for AMDR01EY030443 · NEI · UNIVERSITY OF MARYLAND BALTIMORE · PI THOMPSON, RICHARD BLAIR · 2020 to 2023
$2.1M
Deutsche Forschungsgemeinschaft DFGNEI NIH HHS R01 EY030443
6 · The paper itself

Abstract

Herein, we report the third generation of fluorescent probes (arylphosphonic acids) to target calcifications, particularly hydroxyapatite (HAP). In this study, we use highly conjugated porphyrin-based arylphosphonic acids and their diesters, namely 5,10,15,20-tetrakis[m-(diethoxyphosphoryl)phenyl]porphyrin (m-H

Indexed as

Alzheimer's diseasecalcificationsfluorescent imagingligand synthesisvascular calcifications

Identifiers

PMID32293767
PMCPMC7496659
OpenAlexW3015467921

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.