ArticleeLife2020
Cortical anchoring of the microtubule cytoskeleton is essential for neuron polarity.
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Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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32citing papers in PubMed
–field-weighted citation impact
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Who cites it
32 citing papers in PubMed.
- External mechanical force drives axonal cytoskeletal rearrangements.Current biology : CB · 2026Article
- Auxin-inducible degradation of UNC-116 in C. elegans inhibits bidirectional dense core vesicle transport and worm locomotion on different timescales.Journal of cell science · 2026Article
- IGF-like growth factors that couple food sensing to developmental decisions employ different release mechanisms in a single pair ofbioRxiv : the preprint server for biology · 2026Article
- Polarity reversal of stable microtubules during neuronal development.Journal of cell science · 2025Article
- Kinesins inOpen biology · 2025Review
- Obstacles Regulate Membrane Tension Propagation to Enable Localized Mechanotransduction.bioRxiv : the preprint server for biology · 2025Article
- Axonal Mechanotransduction Drives Cytoskeletal Responses to Physiological Mechanical Forces.bioRxiv : the preprint server for biology · 2025Article
- The kinetochore protein KNL-1 regulates the actin cytoskeleton to control dendrite branching.The Journal of cell biology · 2025Article
- Parallelized Mechanical Stimulation of Neuronal Calcium Through Cell-Internal Nanomagnetic Forces Provokes Lasting Shifts in the Network Activity State.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Multimodal Characterization of Cortical Neuron Response to Permanent Magnetic Field Induced Nanomagnetic Force Maps.ACS nano · 2024Article
- KLP-7/Kinesin-13 orchestrates axon-dendrite checkpoints for polarized trafficking in neurons.Molecular biology of the cell · 2024Article
- Dendrite morphogenesis in Caenorhabditis elegans.Genetics · 2024Review
- CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly.PLoS genetics · 2024Article
- Optimization of RNAi efficiency in PVD neuron of C. elegans.PloS one · 2024Article
- The role of mechanics in axonal stability and development.Seminars in cell & developmental biology · 2023Review
- TheFrontiers in physiology · 2023Article
- Local changes in microtubule network mobility instruct neuronal polarization and axon specification.Science advances · 2022Article
- PTRN-1 (CAMSAP) and NOCA-2 (NINEIN) are required for microtubule polarity in Caenorhabditis elegans dendrites.PLoS biology · 2022Article
- The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.International journal of molecular sciences · 2022Article
- TIAM-1 differentially regulates dendritic and axonal microtubule organization in patterning neuronal development through its multiple domains.PLoS genetics · 2022Article
Corrections and comments
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Authors and funding
15 authors.
Liu HeCell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Utrecht, Netherlands.
Robbelien Kooistra *Cell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Utrecht, Netherlands.ORCID 0000-0003-4576-8964
Ravi Das *Neurophotonics and Mechanical Systems Biology, ICFO-Institut de Ciencies Fotoniques, The Barcelona Institute of Science and Technology, Barcelona, Spain.
Ellen Oudejans *Cell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Utrecht, Netherlands.
Eric van LeenCell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Utrecht, Netherlands.
Johannes ZieglerFast live-cell superresolution microscopy, ICFO-Institut de Ciencies Fotoniques, The Barcelona Institute of Science and Technology, Barcelona, Spain.
Sybren PortegiesCell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Utrecht, Netherlands.
Bart de HaanCell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Utrecht, Netherlands.
Anna van Regteren AltenaCell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Utrecht, Netherlands.
Riccardo StucchiCell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Utrecht, Netherlands.
Af Maarten AltelaarBiomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, Netherlands.
Stefan WieserFast live-cell superresolution microscopy, ICFO-Institut de Ciencies Fotoniques, The Barcelona Institute of Science and Technology, Barcelona, Spain.
Michael KriegNeurophotonics and Mechanical Systems Biology, ICFO-Institut de Ciencies Fotoniques, The Barcelona Institute of Science and Technology, Barcelona, Spain.
Casper C HoogenraadCell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Utrecht, Netherlands.
Martin HarterinkCell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Utrecht, Netherlands.ORCID 0000-0002-8256-6651
Funding
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5MEuropean Research Council 617050European Research Council 715243Generalitat de Catalunya AGAUR 2017 SGR 101H2020 Marie Skłodowska-Curie Actions 754510Human Frontier Science Program CDA00023/2018Ministry of Economy and Competitiveness RYC-2015-17935Ministry of Economy and Competitiveness SEV-20150522Nederlandse Organisatie voor Wetenschappelijk Onderzoek 863.12.00Nederlandse Organisatie voor Wetenschappelijk Onderzoek 865.10.010NIH HHS P40 OD010440
Abstract
The development of a polarized neuron relies on the selective transport of proteins to axons and dendrites. Although it is well known that the microtubule cytoskeleton has a central role in establishing neuronal polarity, how its specific organization is established and maintained is poorly understood. Using the in vivo model system
Indexed as
AnimalsAnkyrinsCaenorhabditis elegansCaenorhabditis elegans ProteinsCell PolarityCells, CulturedCerebral CortexCytoskeletonLocomotionMicrotubulesNerve Growth FactorsNerve Tissue ProteinsNeuronsAnkyrinsCaenorhabditis elegans ProteinsNerve Growth FactorsNerve Tissue ProteinsUNC-119 protein, C elegansunc-33 protein, C elegansunc-44 protein, C elegansAnkyrinC. eleganscell biologyCRMPkinesinmicrotubuleneuron polarityneuroscience
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.