Evidence map›Paper›PMID 32293435›Full record

ArticleBMC biology2020

Multiple links between 5-methylcytosine content of mRNA and translation.

Ulrike Schumann, He-Na Zhang, Tennille Sibbritt, Anyu Pan, Attila Horvath, Simon Gross, Susan J Clark, Li Yang, Thomas Preiss

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 178 citations in OpenAlex.

  1. mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
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  7. mBiology direct · 2026
    Review
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  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. ALYREF condensation stabilizes mThe EMBO journal · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. NSUN2-mediated mJournal of diabetes investigation · 2025
    Article
  20. Article

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Ulrike SchumannEMBL-Australia Collaborating Group, Department of Genome Sciences, John Curtin School of Medical Research, Australian National University, Canberra, 2601, Australian Captial Territory, Australia.
He-Na ZhangCAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.
Tennille SibbrittEMBL-Australia Collaborating Group, Department of Genome Sciences, John Curtin School of Medical Research, Australian National University, Canberra, 2601, Australian Captial Territory, Australia.
Anyu PanEMBL-Australia Collaborating Group, Department of Genome Sciences, John Curtin School of Medical Research, Australian National University, Canberra, 2601, Australian Captial Territory, Australia.
Attila HorvathEMBL-Australia Collaborating Group, Department of Genome Sciences, John Curtin School of Medical Research, Australian National University, Canberra, 2601, Australian Captial Territory, Australia.
Simon GrossEMBL-Australia Collaborating Group, Department of Genome Sciences, John Curtin School of Medical Research, Australian National University, Canberra, 2601, Australian Captial Territory, Australia.
Susan J ClarkGenomics and Epigenetics Division, Garvan Institute of Medical Research, Sydney, 2010, New South Wales, Australia.
Li YangCAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.
Thomas PreissEMBL-Australia Collaborating Group, Department of Genome Sciences, John Curtin School of Medical Research, Australian National University, Canberra, 2601, Australian Captial Territory, Australia. thomas.preiss@anu.edu.au.
Australian National University · AUShanghai Institute of Nutrition and Health · CNShanghai Institutes for Biological Sciences · CNUNSW Sydney · AUVictor Chang Cardiac Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background5-Methylcytosine (m

resultsWe obtained ~ 1000 candidate m

conclusionsOur findings emphasise the major role of NSUN2 in placing the m

Indexed as

Protein Biosynthesis5-MethylcytosineHeLa CellsHumansPolyribosomesRNA, Messenger5-MethylcytosineRNA, Messenger5-MethylcytosineBisulfite conversionBisulfite RNA-seqEpitranscriptomemRNA translationNSUN2PolysomeRNA methylationRNA stabilityTRDMT1

Identifiers

PMID32293435
PMCPMC7158060
OpenAlexW3016045502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.