Evidence map›Paper›PMID 32293351›Full record

ArticleBMC ophthalmology2020

Outcome of intravitreal bevacizumab injection without pre and postoperative antibiotics.

Ruchi Shrestha, Pratap Karki, Sagun Narayan Joshi

Abstract read
In one paragraph

Article in BMC ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Recent Updates on the Diagnosis and Management of Age-Related Macular Degeneration.Mayo Clinic proceedings. Innovations, quality & outcomes · 2024
    Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ruchi ShresthaReiyukai Eiko Masunaga Eye Hospital, Kavre, Banepa, Nepal. drruchishrestha@gmail.com.
Pratap KarkiDepartment of Retina B. P Koirala Lions Centre for Ophthalmic Studies (BPKLCOS), Maharajgunj, Kathmandu, Nepal.
Sagun Narayan JoshiDepartment of Retina, B.PKoirala Lions Centre for Ophthalmic Studies (BPKLCOS), Maharajgunj, Kathmandu, Nepal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgoundIntravitreal injections are the most common treatment modality for several retinal pathologies. Despite endophthalmitis being the most feared complication, antibioprophylaxis remains controversial in intravitreal injections.

methodsThis was a retrospective study done for a period of 2 years from 1st January 2017 to 31st December 2018 in B. P Koirala Lions Centre for Ophthalmic Studies (BPKLCOS) among patients receiving intravitreal bevacizumab. The intravitreal injection was given by a single surgeon. It included 503 eyes which received intravitreal bevacizumab over a period of 2 years without pre and postoperative antibiotics.

resultsOut of 503 eyes studied over a period of 2 years without antibiotic prophylaxis the rate of endophthalmitis was 0.0019% which is very low compared to the other studies with rate of endophthalmitis between 0.019-0.09%.

conclusionThe risk of endophthalmitis was low even without pre/post-operative antibiotics. Intravitreal injection can be given safely without pre-operative and post-operative antibiotics. Trial Registration not applicable as it is a retrospective study.

Indexed as

Antibiotic ProphylaxisAdultAgedAged, 80 and overAngiogenesis InhibitorsBevacizumabChoroid DiseasesEndophthalmitisFemaleFluoroquinolonesHumansIntravitreal InjectionsMaleMiddle AgedRetinal DiseasesRetrospective StudiesAngiogenesis InhibitorsBevacizumabFluoroquinolonesVascular Endothelial Growth Factor AVEGFA protein, humanBevacizumabEndophthalmitisPost-operative antibioticsPre-operative antibiotics

Identifiers

PMID32293351
PMCPMC7161301

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.