Evidence map›Paper›PMID 32293257›Full record

ArticleBMC microbiology2020

Genetic and virulence characterisation of Vibrio parahaemolyticus isolated from Indian coast.

Divya Meparambu Prabhakaran, Thandavarayan Ramamurthy, Sabu Thomas

Open access · goldAbstract read
In one paragraph

Article in BMC microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Divya Meparambu PrabhakaranCholera and Biofilm Research Lab, Department of Pathogen Biology, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, 695 014, India.
Thandavarayan RamamurthyCentre for Human Microbial Ecology, Translational Health Science and Technology Institute, Faridabad, India.
Sabu ThomasCholera and Biofilm Research Lab, Department of Pathogen Biology, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, 695 014, India. sabu@rgcb.res.in.
Rajiv Gandhi Centre for Biotechnology · INTranslational Health Science and Technology Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundV. parahaemolyticus is autochthonous to the marine environment and causes seafood-borne gastroenteritis in humans. Generally, V. parahaemolyticus recovered from the environment and/or seafood is thought to be non-pathogenic and the relationship between environmental isolates and acute diarrhoeal disease is poorly understood. In this study, we explored the virulence potential of environmental V. parahaemolyticus isolated from water, plankton and assorted seafood samples collected from the Indian coast.

resultsTwenty-two V. parahaemolyticus isolates from seafood harboured virulence associated genes encoding the thermostable-direct haemolysin (TDH), TDH-related haemolysin (TRH), and Type 3 secretion systems (T3SS) and 95.5% of the toxigenic isolates had pandemic strain attributes (toxRS/new

conclusionOur study provides evidence that environmental isolates of V. parahaemolyticus are potentially invasive and capable of eliciting pathogenic characteristics typical of clinical strains and present a potential health risk. We also demonstrate that virulence of this pathogen is highly complex and hence draws attention for the need to investigate more reliable virulence markers in order to distinguish the environmental and clinical isolates, which will be crucial for the pathogenomics and control of this pathogen.

Indexed as

Actin CytoskeletonBacterial ProteinsBacterial ToxinsCaco-2 CellsHemolysin ProteinsHumansIndiaPhylogenyPlanktonSeafoodType III Secretion SystemsVibrio InfectionsVibrio parahaemolyticusVirulence FactorsWater MicrobiologyZonula Occludens-1 ProteinBacterial ProteinsBacterial ToxinsHemolysin Proteinsthermostable direct hemolysinthermostable direct hemolysin-related hemolysin protein, Vibrio parahaemolyticusTJP1 protein, humanType III Secretion SystemsVirulence FactorsZonula Occludens-1 ProteinCytotoxicityInvasionPandemic traitsPulsed-field gel electrophoresisSeafoodType 3 secretion systemV. parahaemolyticus

Identifiers

PMID32293257
PMCPMC7092547
OpenAlexW3026470111

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.