Evidence map›Paper›PMID 32292715›Full record

ArticleFrontiers in oncology2020

Ephrin-B1 Is a Novel Biomarker of Bladder Cancer Aggressiveness. Studies in Murine Models and in Human Samples.

María Victoria Mencucci, Lara Lapyckyj, Marina Rosso, María José Besso, Denise Belgorosky, Mariana Isola, Silvia Vanzulli, Catalina Lodillinsky, Ana María Eiján, Juan Carlos Tejerizo and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

María Victoria MencucciLaboratorio de Estudios de la Interacción Celular en Reproducción y Cáncer, Instituto de Biología y Medicina Experimental (IBYME; CONICET-FIBYME), Buenos Aires, Argentina.
Lara LapyckyjLaboratorio de Estudios de la Interacción Celular en Reproducción y Cáncer, Instituto de Biología y Medicina Experimental (IBYME; CONICET-FIBYME), Buenos Aires, Argentina.
Marina RossoLaboratorio de Estudios de la Interacción Celular en Reproducción y Cáncer, Instituto de Biología y Medicina Experimental (IBYME; CONICET-FIBYME), Buenos Aires, Argentina.
María José BessoLaboratorio de Estudios de la Interacción Celular en Reproducción y Cáncer, Instituto de Biología y Medicina Experimental (IBYME; CONICET-FIBYME), Buenos Aires, Argentina.
Denise BelgoroskyResearch Area, Instituto de Oncología Angel H. Roffo, Universidad de Buenos Aires, Buenos Aires, Argentina.
Mariana IsolaDepartamento de Anatomía Patológica, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Silvia VanzulliAcademia Nacional de Medicina, Buenos Aires, Argentina.
Catalina LodillinskyResearch Area, Instituto de Oncología Angel H. Roffo, Universidad de Buenos Aires, Buenos Aires, Argentina.
Ana María EijánResearch Area, Instituto de Oncología Angel H. Roffo, Universidad de Buenos Aires, Buenos Aires, Argentina.
Juan Carlos TejerizoDepartamento de Urología, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Matías Ignacio GonzalezDepartamento de Urología, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
María Ercilia ZubietaDepartamento de Urología, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Mónica Hebe Vazquez-LevinLaboratorio de Estudios de la Interacción Celular en Reproducción y Cáncer, Instituto de Biología y Medicina Experimental (IBYME; CONICET-FIBYME), Buenos Aires, Argentina.
Hospital Italiano de Buenos Aires · ARConsejo Nacional de Investigaciones Científicas y Técnicas · ARUniversity of Buenos Aires · ARExperimental Medicine and Biology Institute · ARAcademia Nacional de Medicina · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bladder cancer (BC) is the ninth most common cancer worldwide, but molecular changes are still under study. During tumor progression, Epithelial cadherin (E-cadherin) expression is altered and β-catenin may be translocated to the nucleus, where it acts as co-transcription factor of tumor invasion associated genes. This investigation further characterizes E-cadherin and β-catenin associated changes in BC, by combining bioinformatics, an experimental murine cell model (MB49/MB49-I) and human BC samples. In

Indexed as

beta-cateninbiomarkerbladder cancerEphrin-B1epithelial cadherin

Identifiers

PMID32292715
PMCPMC7119101
OpenAlexW3013085418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.