Evidence map›Paper›PMID 32292659›Full record

ArticlePeerJ2020

First de novo whole genome sequencing and assembly of the bar-headed goose.

Wen Wang, Fang Wang, Rongkai Hao, Aizhen Wang, Kirill Sharshov, Alexey Druzyaka, Zhuoma Lancuo, Yuetong Shi, Shuo Feng

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Article in PeerJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Wen WangState Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xi'ning, Qinghai, China.
Fang WangNorthwest Institute of Plateau Biology, Chinese Academy of Sciences, Xi'ning, Qinghai, China.
Rongkai HaoNovogene Bioinformatics Institute, Beijing, China.
Aizhen WangCollege of Eco-Environmental Engineering, Qinghai University, Xi'ning, Qinghai, China.
Kirill SharshovResearch Institute of Experimental and Clinical Medicine, Novosibirsk, Russia.
Alexey DruzyakaInstitute of Systematics and Ecology of Animals, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.
Zhuoma LancuoSchool of Finance and Economics, Qinghai University, Xi'ning, Qinghai, China.
Yuetong ShiKunLun College of Qinghai University, Xi'ning, Qinghai, China.
Shuo FengState Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xi'ning, Qinghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe bar-headed goose (

methodsIn this study, we present the first de novo whole genome sequencing and assembly of the bar-headed goose, along with gene prediction and annotation.

results10X Genomics sequencing produced a total of 124 Gb sequencing data, which can cover the estimated genome size of bar-headed goose for 103 times (average coverage). The genome assembly comprised 10,528 scaffolds, with a total length of 1.143 Gb and a scaffold N50 of 10.09 Mb. Annotation of the bar-headed goose genome assembly identified a total of 102 Mb (8.9%) of repetitive sequences, 16,428 protein-coding genes, and 282 tRNAs. In total, we determined that there were 63 expanded and 20 contracted gene families in the bar-headed goose compared with the other 15 vertebrates. We also performed a positive selection analysis between the bar-headed goose and the closely related low-altitude goose, swan goose (

conclusionWe reported the currently most complete genome sequence of the bar-headed goose. Our assembly will provide a valuable resource to enhance further studies of the gene functions of bar-headed goose. The data will also be valuable for facilitating studies of the evolution, population genetics and high-altitude adaptations of the bar-headed geese at the genomic level.

Indexed as

10X Genomics ChromiumAnser indicusAvian genomesBar-headed gooseComparative genomicsConservation genomicsHigh-altitude adaptationHypoxiaPositive selectionQinghai-Tibetan Plateau

Identifiers

PMID32292659
PMCPMC7144584

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.