Evidence map›Paper›PMID 32292596›Full record

ArticleImmunometabolism2020

Commentary on Camell et al., Aging Induces Nlrp3 Inflammasome Dependent Adipose B Cell Expansion to Impair Metabolic Homeostasis.

Sara SantaCruz-Calvo, Lucia SantaCruz-Calvo, Barbara S Nikolajczyk

Abstract readComment
In one paragraph

Article in Immunometabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Sara SantaCruz-CalvoDepartment of Pharmacology and Nutritional Sciences, Barnstable Brown Diabetes and Obesity Research Center, University of Kentucky, Lexington, KY 40536, USA.
Lucia SantaCruz-CalvoDepartment of Chemistry and Food Technology, Technical University of Madrid, Madrid 28040, Spain.
Barbara S NikolajczykDepartment of Pharmacology and Nutritional Sciences, Barnstable Brown Diabetes and Obesity Research Center, University of Kentucky, Lexington, KY 40536, USA.

Funding

Inflammation in human obesity and type 2 diabetesR01DK108056 · NIDDK · UNIVERSITY OF KENTUCKY · PI LAUFFENBURGER, DOUGLAS A, NIKOLAJCZYK, BARBARA · 2016 to 2019
$2.6M
NIDDK NIH HHS R01 DK108056
6 · The paper itself

Abstract

The burden of aging and obesity is urging extended investigation into the molecular mechanisms that underlie chronic adipose tissue inflammation. B cell-targeted therapies are emerging as novel tools to modulate the immune system and thereby mitigate aging and obesity-related metabolic complications.

Indexed as

adipose tissueagingB cellsFALCinflammationobesity

Identifiers

PMID32292596
PMCPMC7156147

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.