Evidence map›Paper›PMID 32292521›Full record

ArticleTheranostics2020

Tumor reoxygenation for enhanced combination of radiation therapy and microwave thermal therapy using oxygen generation in situ by CuO nanosuperparticles under microwave irradiation.

Zengzhen Chen, Wenna Guo, Qiong Wu, Longfei Tan, Tengchuang Ma, Changhui Fu, Jie Yu, Xiangling Ren, Jianming Wang, Ping Liang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Endogenous HInternational journal of nanomedicine · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Zengzhen ChenLaboratory of Controllable Preparation and Application of Nanomaterials, Key Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, No. 29 East Road Zhongguancun, Beijing 100190, People's Republic of China.
Wenna GuoLaboratory of Controllable Preparation and Application of Nanomaterials, Key Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, No. 29 East Road Zhongguancun, Beijing 100190, People's Republic of China.
Qiong WuLaboratory of Controllable Preparation and Application of Nanomaterials, Key Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, No. 29 East Road Zhongguancun, Beijing 100190, People's Republic of China.
Longfei TanLaboratory of Controllable Preparation and Application of Nanomaterials, Key Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, No. 29 East Road Zhongguancun, Beijing 100190, People's Republic of China.
Tengchuang MaDepartment of Nuclear Medicine, Harbin Medical University Cancer Hospital, Harbin 150086, People's Republic of China.
Changhui FuLaboratory of Controllable Preparation and Application of Nanomaterials, Key Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, No. 29 East Road Zhongguancun, Beijing 100190, People's Republic of China.
Jie YuDepartment of Interventional Ultrasound, Chinese PLA General Hospital, Beijing 100853, People's Republic of China.
Xiangling RenLaboratory of Controllable Preparation and Application of Nanomaterials, Key Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, No. 29 East Road Zhongguancun, Beijing 100190, People's Republic of China.
Jianming WangBeijing Institute of Fashion Technology. No. A2, East Yinghua Street, Chaoyang District, Beijing 102209, People's Republic of China.
Ping LiangDepartment of Interventional Ultrasound, Chinese PLA General Hospital, Beijing 100853, People's Republic of China.
Xianwei MengLaboratory of Controllable Preparation and Application of Nanomaterials, Key Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, No. 29 East Road Zhongguancun, Beijing 100190, People's Republic of China.
Chinese PLA General Hospital · CNUniversity of Chinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As known, radiation therapy (RT) can exacerbate the degree of hypoxia of tumor cells, which induces serious resistance to RT and in turn, is the greatest obstacle to RT. Reoxygenation can restore the hypoxic state of tumor cells, which plays an important role in reshaping tumor microenviroment for achieving optimal therapeutic efficacy. Herein, we report for the first time that microwave (MW)-triggered IL-Quercetin-CuO-SiO

Indexed as

AnimalsCase-Control StudiesCombined Modality TherapyCopperDown-RegulationHumansHyperthermia, InducedHypoxia-Inducible Factor 1, alpha SubunitMiceMice, Inbred BALB CMicrowavesNanoparticlesNeoplasmsOxygenRadiotherapySilicon DioxideCoppercupric oxideHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitOxygenSilicon Dioxidemicrowaveradiation therapyreoxygenationthermal therapytumor

Identifiers

PMID32292521
PMCPMC7150478
OpenAlexW3015533915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.