ArticlePakistan journal of medical sciences
Role of Methyl Prednisolone in Longitudinal Extensive Transverse Myelitis (LETM) in Children.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Beware of the Pediatric Limp: A Case ofJournal of education & teaching in emergency medicine · 2025Article
- Early Therapeutic Plasma Exchange in Pediatric Transverse Myelitis: A Case Report and Scoping Review.Neurology international · 2024Article
- 'A kiss that took my legs away': a rare presentation of Epstein-Barr virus in the older population.Clinical medicine (London, England) · 2023Article
- Encephalomyelitis associated with coronavirus disease 2019: a case report.Journal of medical case reports · 2022Article
- Extensive Longitudinal Transverse Myelitis Associated With CSF Epstein-Barr Virus Infection: A Case Report.Child neurology openArticle
- Longitudinally extensive transverse myelitis following ChAdOx1 nCoV-19 vaccine.Journal of postgraduate medicineArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe role of methyl prednisolone in longitudinal extensive transverse myelitis in children is not completely discovered in developing country like Pakistan. So this is the first study which aimed to evaluate the efficacy of methyl prednisolone in longitudinal extensive transverse myelitis in children.
methodsThis is quasi experimental hospital based descriptive prospective study. The data was collected from 34 children admitted in Paediatric Neurology department through Outpatient/emergency department in Children's Hospital and the Institute of Child Health, Lahore for period of one year from January 2018 to December 2018. The children full filling the inclusion criteria were observed before and after giving injection methyl prednisolone 30mg/kg/dose (maximum dose one Gram irrespective of the body weight) once daily for five days in the form of intravenous infusion.
resultsComplete recovery was seen in 41.2% while 58.8% showed partial recovery. The correlation of response to treatment (recovery) with gender, area of spinal cord involvement, muscle power and autonomic dysfunction is found at significance level of five percent according to Chi square test.
conclusionEarly consideration and administration of methyl prednisolone in longitudinally extensive transverse myelitis in children can be beneficial and can help to reduce the morbidity.
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