ArticlePakistan journal of medical sciences
Bronchial lavage under fiberoptic bronchoscopy in the treatment of severe pulmonary infection.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Effects of Esketamine-Dexmedetomidine Combination on Immediate Postprocedural Oxygenation Index in Severe Pneumonia Patients Undergoing Bedside Fiberoptic Bronchoscopic Sputum Aspiration: A Prospective Randomised Controlled Trial.Drug design, development and therapy · 2025Trial
- Comparison of remifentanil and esketamine in combination with propofol for patient sedation during fiberoptic bronchoscopy.BMC pulmonary medicine · 2023Trial
- Unlocking the potential of bronchoalveolar lavage: a promising supplement therapy for moderate-to-severe allergic asthma.BMC pulmonary medicine · 2026Article
- Role of early bedside bronchoscopy-assisted sputum aspiration in the treatment of pneumonia in stroke patients.Frontiers in medicine · 2026Article
- Effect of bronchoalveolar lavage combined with high-dose ambroxol hydrochloride on severe pneumonia with respiratory failure.American journal of translational research · 2025Article
- Clinical observations of high-flow nasal cannula oxygenation in endobronchial ultrasound-guided transbronchial needle aspiration: a randomized controlled study.Frontiers in medicine · 2025Article
- Effects of acetylcysteine combined with bronchoalveolar lavage under fiberoptic bronchoscopy on blood oxygenation and inflammation in elderly severe pneumonia patients.American journal of translational research · 2025Article
- Cytopathological analysis of bronchoalveolar lavage fluid in patients with and without HIV infection.BMC pulmonary medicine · 2022Article
- Clinical significance of procalcitonin in critically ill patients with pneumonia receiving bronchoalveolar lavage.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2022Article
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4 authors at 1 institution in 1 country.
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Abstract
objectiveTo investigate the clinical efficacy of bronchial lavage under fiberoptic bronchoscopy in the treatment of severe pulmonary infection.
methodsOne hundred forty eight patients with severe pulmonary infection who were admitted to our hospital from October 2016 to December 2017 were included in this study. According to the random number table method, they were divided into a control group and an observation group with 79 patients each. The control group was given conventional treatment, while the observation group was given bronchoalveolar lavage with fiberoptic bronchoscopy on the basis of the treatment in the control group. The clinical efficacy of the two groups was compared, the duration of mechanical ventilation, antibiotic use and symptoms improvement of the two groups were recorded, and the respiratory mechanics parameters, serum procalcitonin (PCT) and transforming growth factor β (TGF-β) level were measured before and after treatment.
resultsThe duration of mechanical ventilation, antibiotic use, respiratory failure correction, body temperature decline and white blood cell recovery in the observation group were significantly shorter than those in the control group (P<0.05). The total efficacy of the observation group was significantly higher than that of the control group (92.4% vs. 74.7%). The respiratory mechanics parameters of the two groups after treatment were higher than those before treatment (P<0.05) and the increase of the observation group was more obvious than that of the control group (P<0.05). The serum PCT and TGF-β levels of the two groups after treatment were lower than those before treatment (P<0.05), and the decrease level in the observation group was more obvious (P<0.05).
conclusionBronchial lavage under fiberoptic bronchoscopy can improve the clinical efficacy, accelerate the improvement of clinical symptoms and respiratory mechanics parameters, significantly reduce the PCT and TGF-β levels, and promote the rapid recovery of patients in the treatment of severe pulmonary infection.
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