Evidence map›Paper›PMID 32291723›Full record

ArticleJournal of general internal medicine2020

Opioid Agonist Therapy During Hospitalization Within the Veterans Health Administration: a Pragmatic Retrospective Cohort Analysis.

Kelsey C Priest, Travis I Lovejoy, Honora Englander, Sarah Shull, Dennis McCarty

Open access · bronzeAbstract read
In one paragraph

Article in Journal of general internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 3 pooled it
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 3 syntheses or guidelines pooled it, 76 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Review
  8. Observational
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Kelsey C PriestSchool of Medicine, MD/PhD Program, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Mail Code: L357, Portland, OR, 97239, USA. priest@ohsu.edu.
Travis I LovejoySchool of Public Health, Oregon Health & Science University-Portland State University, Portland, OR, USA.
Honora EnglanderDivision of Hospital Medicine & Section of Addiction Medicine, Department of Medicine, Oregon Health & Science University, Portland, OR, USA.
Sarah ShullCenter to Improve Veteran Involvement in Care, VA Portland Health Care System, Portland, OR, USA.
Dennis McCartySchool of Public Health, Oregon Health & Science University-Portland State University, Portland, OR, USA.
Oregon Health & Science University · USPortland State University · USVA Portland Health Care System · US

Funding

Western States Node of the National Drug Abuse Treatment Clinical Trials Network (TMS for CUD) UG1DA015815 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Keith N. Humphreys, Philip Todd Korthuis · 2015 to 2026
$24.6M
Oregon's Coordinated Care Organizations Integrate Care for Drug Use DisordersR33DA035640 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI LIND, BONNIE · 2014 to 2017
$2.4M
Variation in the Use of Opioid Agonist Treatment in HospitalsF30DA044700 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI PRIEST, KELSEY CAROLINE · 2017 to 2020
$186k
Chronic Pain Management in Veterans with Co-occurring Substance Use DisordersIK2HX001516 · VA · PORTLAND VA MEDICAL CENTER · PI LOVEJOY, TRAVIS IAN · 2015 to 2019
–
CA 2 BLOCKERS AND CATECHOL REUPTAKE INHIBITORSR01DA004470 · NIDA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI NAHAS, GABRIEL G · 1987 to 1989
–
HSRD VA IK2 HX001516NIDA NIH HHS F30 DA044700NIDA NIH HHS F30 DA044700UGNIDA NIH HHS R33 DA035640NIDA NIH HHS UG1 DA015815VA IK2HX001516
6 · The paper itself

Abstract

backgroundHospitalization of patients with opioid use disorder (OUD) is increasing, yet little is known about opioid agonist therapy (OAT: methadone and buprenorphine) administration during admission.

objectiveDescribe and examine patient- and hospital-level characteristics associated with OAT receipt during hospitalization in the Veterans Health Administration (VHA).

participantsA total of 12,407 unique patients, ≥ 18 years old, with an OUD-related ICD-10 diagnosis within 12 months prior to or during index hospitalization in fiscal year 2017 from 109 VHA hospitals in the continental U.S. MAIN MEASURE: OAT received during hospitalization. KEY

resultsFew admissions received OAT (n = 1914; 15%) and when provided it was most often for withdrawal management (n = 834; 7%). Among patients not on OAT prior to admission who survived hospitalization (n = 10,969), 2.0% (n = 203) were newly initiated on OAT with linkage to care after hospital discharge. Hospitals varied in the frequency of OAT delivery (range, 0 to 43% of qualified admissions). Patients with pre-admission OAT (adjusted odds ratio [AOR] = 15.30; 95% CI [13.2, 17.7]), acute OUD diagnosis (AOR = 2.3; 95% CI [1.99, 2.66]), and male gender (AOR 1.52; 95% CI [1.16, 2.01]) had increased odds of OAT receipt. Patients who received non-OAT opioids (AOR 0.53; 95% CI [0.46, 0.61]) or surgical procedures (AOR 0.75; 95% CI [0.57, 0.99]) had decreased odds of OAT receipt. Large-sized (AOR = 2.0; 95% CI [1.39, 3.00]) and medium-sized (AOR = 1.9; 95% CI [1.33, 2.70]) hospitals were more likely to provide OAT.

conclusionsIn a sample of VHA inpatient medical admissions, OAT delivery was infrequent, varied across the health system, and was associated with specific patient and hospital characteristics. Policy and educational interventions should promote hospital-based OAT delivery.

Indexed as

Analgesics, OpioidOpioid-Related DisordersAdolescentCohort StudiesHospitalizationHumansMaleOpiate Substitution TreatmentRetrospective StudiesVeterans HealthAnalgesics, Opioidbuprenorphinehospital medicinemethadoneopioid agonist therapyopioid use disorder

Identifiers

PMID32291723
PMCPMC7403377
OpenAlexW3015890779

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.