Evidence map›Paper›PMID 32291364›Full record

ArticleJournal of research in health sciences2020

Application of Multi-State Model in Analyzing of Breast Cancer Data.

Mahtab Vasheghani Farahani, Parisa Ataee Dizaji, Hamid Rashidi, Fariborz Mokarian, Akbar Biglarian

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Article in Journal of research in health sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Mahtab Vasheghani FarahaniDepartment of Biostatistics, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Parisa Ataee DizajiDepartment of Biostatistics, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Hamid RashidiDepartment of Biostatistics, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Fariborz MokarianFaculty of Medicine, Cancer Prevention Research Center, Isfahan University of Medical Sciences, Iran.
Akbar BiglarianDepartment of Biostatistics, Social Determinants of Health Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. abiglarian@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe multistate model is used generally to fit the longitudinal data. This model can determine the natural trend of disease progress in different states of treatment, recuperate, metastasis and finally death. We aimed to use multistate models in order to analyzing breast cancer (BC) data. STUDY

designA historical cohort study.

methodsIn this historical cohort study, 573 women with BC were studied. These patients were referred to Isfahan Sayed-o-Shohada Hospital during 1999-2006 and followed up to Apr 2017. The corresponding provided data were gathered by Isfahan Cancer Prevention Center. Then data analyzed by multistate models in R 3.4.1 software.

resultsThe mean and standard deviation of women age were 47.19±10.77 years. The transition probability from state of first treatment to recuperate state was 71%, to metastasis state 2% and to death was 16%. The sojourn time in different states of disease was 2.39 yr for first treatment, 6.93 yr for recuperate and 0.16 yr for death.

conclusionThis model is able to predict the transition probabilities in different state of disease, so its results are useful for clinical researches. In addition, with transition probabilities and also survival mean in each state in hand, the physicians will be able to suggest suitable treatment plans for patients.

Indexed as

Breast NeoplasmsData AnalysisAdultDisease ProgressionFemaleHospitalsHumansIranLength of StayMarkov ChainsMiddle AgedModels, StatisticalRetrospective StudiesRisk AssessmentRisk FactorsSurvival AnalysisBreast cancerMultistate modelSurvival analysis

Identifiers

PMID32291364
PMCPMC7183561

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