Evidence map›Paper›PMID 32291349›Full record

ArticlemSystems2020

Selective Upregulation of Transcripts for Six Molecules Related to T Cell Costimulation and Phagocyte Recruitment and Activation among 734 Immunity-Related Genes in the Brain during Perforin-Dependent, CD8

Jenny Lutshumba, Eri Ochiai, Qila Sa, Namrata Anand, Yasuhiro Suzuki

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Infection and immunity · 2024
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  11. Identification of novel biomarkers for anti-Frontiers in microbiology · 2024
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  12. Review
  13. Article
  14. The role of IL-1 family of cytokines and receptors in pathogenesis of COVID-19.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2022
    Article
  15. CircRNA and miRNA expression analysis in livers of mice withFrontiers in cellular and infection microbiology · 2022
    Article
  16. Review
  17. Review
  18. Key Limitations and New Insights Into theFrontiers in cellular and infection microbiology · 2020
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jenny LutshumbaDepartment of Microbiology, Immunology and Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Eri OchiaiDepartment of Microbiology, Immunology and Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Qila SaDepartment of Microbiology, Immunology and Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Namrata AnandDepartment of Microbiology, Immunology and Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Yasuhiro SuzukiDepartment of Microbiology, Immunology and Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, USA yasu.suzuki@uky.edu.
University of Kentucky · US

Funding

Cooperation of CD8+ T cells and phagocytes to eliminate Toxoplasma cystsR01AI095032 · NIAID · UNIVERSITY OF KENTUCKY · PI SUZUKI, YASUHIRO · 2012 to 2023
$4.1M
Effector molecules for IFN-gamma-mediated prevention of Toxoplasma proliferation in the brainR21AI134323 · NIAID · UNIVERSITY OF KENTUCKY · PI SUZUKI, YASUHIRO · 2017 to 2018
$421k
Gender-dependent innate IL-10 production as a key pathogenic factor to promote toxoplasmic encephalitisR21AI136821 · NIAID · UNIVERSITY OF KENTUCKY · PI SUZUKI, YASUHIRO · 2018 to 2019
$421k
NIAID NIH HHS R01 AI095032NIAID NIH HHS R21 AI134323NIAID NIH HHS R21 AI136821
6 · The paper itself

Abstract

We recently found that an invasion of CD8

Indexed as

CD8+ cytotoxic T cellschemokine receptorcoactivation moleculescostimulatory moleculeslarge-scale gene expression profileperforinphagocytesT cell invasion

Identifiers

PMID32291349
PMCPMC7159899
OpenAlexW3016094068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.