ArticlePlant physiology2020
Insights into the Diversification and Evolution of R2R3-MYB Transcription Factors in Plants.
Article in Plant physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
108 citing papers in PubMed, 209 citations in OpenAlex.
- Evolutionary and functional divergence of MYB regulatory networks in flavonoid biosynthesis across Poaceae, non-Poaceae monocots, and eudicot horticultural plants.Horticulture research · 2026Review
- Article
- Review
- Phytoplasma Effector SJP8 Suppresses Host Immunity by Promoting the Degradation of ZjMYB15 and ZjMYB86-like to Perturb Jasmonic Acid and Hydrogen Peroxide Homeostasis in Jujube.Molecular plant pathology · 2026Article
- Integration of Spatiotemporal Multi-Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome-Mediated Stress Adaptation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Article
- The RcMYB21 transcription factor activates flavonol biosynthesis by targeting RcFLS in Chinese raspberry.BMC plant biology · 2026Article
- Genome-Wide Identification and Characterization of the MYB Transcription Factor Family inGenes · 2026Article
- Long non-coding RNA RsLNC2361 positively regulate anthocyanin accumulation in radish.BMC plant biology · 2026Article
- OsMYB99 Modulates Grain Wax Biosynthesis and Redox Homeostasis to Control Head Rice Yield and Chalkiness.Plant biotechnology journal · 2026Article
- ZmMYB127 Modulates Maize Kernel Texture and Size by Integrating the Synthesis of Starch, Zein Proteins and Auxin.Plant biotechnology journal · 2026Article
- Genome-wide analysis of the MYB gene family and its stress-responsive expression under salinity and drought in sesame.Scientific reports · 2026Article
- A complete telomere-to-telomere genome assembly of Solanum melongena uncovers key regulators in pan-tissue anthocyanin biosynthesis.Plant communications · 2025Article
- Loss-of-function of VrMYB104 in Mungbean hampers growth and multiple adaptive responses under waterlogging stress.Plant cell reports · 2025Article
- Genetic Regulation of Anthocyanin Biosynthesis inPlant direct · 2025Article
- JA-responsive R2R3-type MYB transcription factor OsMYB4P confers broad-spectrum antiviral immunity in rice.Plant biotechnology journal · 2025Article
- Arabidopsis MYB47 and MYB95 transcription factors regulate jasmonate-inducible ER-body formation.Communications biology · 2025Article
- Evolution of short trichomes and long hairs on Nigella petals through co-option of bHLH and non-MIXTA MYB genes.Nature communications · 2025Article
- Mechanisms driving functional divergence of transcription factor paralogs.The New phytologist · 2025Review
- SHOT GLASS, an R2R3-MYB transcription factor, promotes gemma cup and gametangiophore development in Marchantia polymorpha.The New phytologist · 2025Article
48 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As one of the largest families of transcription factors (TFs) in plants, R2R3-MYB proteins play crucial roles in regulating a series of plant-specific biological processes. Although the diversity of plant R2R3-MYB TFs has been studied previously, the processes and mechanisms underlying the expansion of these proteins remain unclear. Here, we performed evolutionary analyses of plant R2R3-MYB TFs with dense coverage of streptophyte algae and embryophytes. Our analyses revealed that ancestral land plants exhibited 10 subfamilies of R2R3-MYB proteins, among which orthologs of seven subfamilies were present in chlorophytes and charophycean algae. We found that asymmetric gene duplication events in different subfamilies account for the expansion of R2R3-MYB proteins in embryophytes. We further discovered that the largest subfamily of R2R3-MYBs in land plants, subfamily VIII, emerged in the common ancestor of Zygnematophyceae and embryophytes. During plant terrestrialization, six duplication events gave rise to seven clades of subfamily VIII. Subsequently, this TF subfamily showed a tendency for expansion in bryophytes, lycophytes, and ferns and extensively diversified in ancestral gymnosperms and angiosperms in clades VIII-A-1, VIII-D, and VIII-E. In contrast to subfamily VIII, other subfamilies of R2R3-MYB TFs have remained less expanded across embryophytes. The findings regarding phylogenetic analyses, auxiliary motifs, and DNA-binding specificities provide insight into the evolutionary history of plant R2R3-MYB TFs and shed light on the mechanisms underlying the extensive expansion and subsequent sub- and neofunctionalization of these proteins.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.