Evidence map›Paper›PMID 32291305›Full record

ArticlemBio2020

The WblC/WhiB7 Transcription Factor Controls Intrinsic Resistance to Translation-Targeting Antibiotics by Altering Ribosome Composition.

Ju-Hyung Lee, Ji-Sun Yoo, Yeonbum Kim, Jong-Seo Kim, Eun-Jin Lee, Jung-Hye Roe

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. WhiB-like proteins: Diversity of structure, function and mechanism.Biochimica et biophysica acta. Molecular cell research · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Beyond antibiotic resistance: thebioRxiv : the preprint server for biology · 2023
    Article
  11. Article
  12. Small molecule inducers of actinobacteria natural product biosynthesis.Journal of industrial microbiology & biotechnology · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ju-Hyung Lee *School of Biological Sciences, Seoul National University, Seoul, South Korea.
Ji-Sun Yoo *School of Biological Sciences, Seoul National University, Seoul, South Korea.
Yeonbum KimSchool of Biological Sciences, Seoul National University, Seoul, South Korea.
Jong-Seo KimSchool of Biological Sciences, Seoul National University, Seoul, South Korea.
Eun-Jin LeeDepartment of Life Sciences, School of Life Sciences and Biotechnology, Korea University, Seoul, South Korea eunjinlee@korea.ac.kr jhroe@snu.ac.kr.ORCID 0000-0001-5078-1974
Jung-Hye RoeSchool of Biological Sciences, Seoul National University, Seoul, South Korea eunjinlee@korea.ac.kr jhroe@snu.ac.kr.
Seoul National University · KRKorea University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteria that encounter antibiotics can efficiently change their physiology to develop resistance. This intrinsic antibiotic resistance is mediated by multiple pathways, including a regulatory system(s) that activates specific genes. In some

Indexed as

Anti-Bacterial AgentsBacterial ProteinsDrug Resistance, Multiple, BacterialGene Expression Regulation, BacterialMicrobial Sensitivity TestsProtein BiosynthesisRegulonRibosomesStreptomyces coelicolorTranscription FactorsAnti-Bacterial AgentsBacterial ProteinsTranscription FactorswhiB protein, Streptomycesantibiotic resistanceribosome-associated proteinsStreptomyces coelicolortranslation-targeting antibioticsWhiB-like protein

Identifiers

PMID32291305
PMCPMC7157823
OpenAlexW3015321043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.