Evidence map›Paper›PMID 32291304›Full record

ArticlemBio2020

EspFu-Mediated Actin Assembly Enhances Enteropathogenic

Fernando H Martins, Ashwani Kumar, Cecilia M Abe, Eneas Carvalho, Milton Nishiyama-Jr, Chao Xing, Vanessa Sperandio, Waldir P Elias

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Pathophysiology of enteropathogenicJournal of veterinary science · 2022
    Review
  5. Two EnteropathogenicJournal of microbiology and biotechnology · 2021
    Article
  6. Pathogenic potential assessment of the Shiga toxin-producingProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  7. Article
  8. Review
  9. Review
  10. Genomic Properties and Temporal Analysis of the Interaction of an InvasiveFrontiers in cellular and infection microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Fernando H MartinsLaboratory of Bacteriology, Butantan Institute, São Paulo, Brazil.
Ashwani KumarEugene McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Cecilia M AbeLaboratory of Bacteriology, Butantan Institute, São Paulo, Brazil.
Eneas CarvalhoLaboratory of Bacteriology, Butantan Institute, São Paulo, Brazil.
Milton Nishiyama-JrLaboratory for Applied Toxinology, Center of Toxins, Immune-Response and Cell Signaling (CeTICS), Butantan Institute, São Paulo, Brazil.
Chao XingEugene McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Vanessa SperandioDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA vanessa.sperandio@utsouthwestern.edu waldir.elias@butantan.gov.br.
Waldir P EliasLaboratory of Bacteriology, Butantan Institute, São Paulo, Brazil vanessa.sperandio@utsouthwestern.edu waldir.elias@butantan.gov.br.ORCID 0000-0003-3470-5706
Instituto Butantan · BRSouthwestern Medical Center · USThe University of Texas Southwestern Medical Center · US

Funding

Quorum sensing regulation of EHEC virulence genesR01AI053067 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI SPERANDIO, VANESSA · 2003 to 2017
$6.3M
Quorum Sensing Regulation of EHEC Virulence GenesR37AI053067 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI VANESSA SPERANDIO · 2018 to 2026
$5.3M
Tryptophan derivatives in EHEC pathogenesisR01AI114511 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI SPERANDIO, VANESSA · 2015 to 2019
$2.3M
Sugar Regulation of EHEC virulenceR01AI105135 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI SPERANDIO, VANESSA · 2013 to 2016
$1.6M
Sugar Regulation of EHEC virulence - A1R56AI105135 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI MARESSO, ANTHONY W, SPERANDIO, VANESSA · 2018 to 2018
$499k
Branched Chain Amino Acid Metabolism During AnthraxR21AI146481 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI MARESSO, ANTHONY W · 2019 to 2020
$440k
NIAID NIH HHS R01 AI053067NIAID NIH HHS R01 AI105135NIAID NIH HHS R01 AI114511NIAID NIH HHS R21 AI146481NIAID NIH HHS R37 AI053067NIAID NIH HHS R56 AI105135
6 · The paper itself

Abstract

The translocation of effectors into the host cell through type 3 secretion systems (T3SS) is a sophisticated strategy employed by pathogenic bacteria to subvert host responses and facilitate colonization. Enteropathogenic

Indexed as

Bacterial AdhesionInflammationActinsAdhesins, BacterialEnteropathogenic Escherichia coliEscherichia coli ProteinsHost-Pathogen InteractionsHumansIntracellular Signaling Peptides and ProteinsPolymerizationSignal TransductionType III Secretion SystemsActinsAdhesins, BacterialEscherichia coli ProteinsEspFU protein, E coliIntracellular Signaling Peptides and ProteinsType III Secretion Systemsenteropathogenic E. coliEspFu/TccPinflammationpedestal formationTir phosphorylation

Identifiers

PMID32291304
PMCPMC7157822
OpenAlexW3015287937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.