Evidence map›Paper›PMID 32291278›Full record

ArticleScience (New York, N.Y.)2020

Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period.

Stephen M Kissler, Christine Tedijanto, Edward Goldstein, Yonatan H Grad, Marc Lipsitch

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,289 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,289citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,289 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Characteristics of subarachnoid hemorrhage associated with COVID-19 infection: A systematic review and descriptive analysis.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023
    Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Final-Size Solutions for SIRI Models with Vaccination.Bulletin of mathematical biology · 2026
    Article
  14. Update on Influenza.The American journal of the medical sciences · 2026
    Review
  15. Susceptible host dynamics explain pathogen resilience to perturbations.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  16. Review
  17. Article
  18. Article
  19. Susceptible host dynamics explain pathogen resilience to perturbations.bioRxiv : the preprint server for biology · 2025
    Article
  20. Article

1,229 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Stephen M Kissler *Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0001-6000-8387
Christine Tedijanto *Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0003-3403-5765
Edward GoldsteinDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-6795-0559
Yonatan H Grad *Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA. mlipsitc@hsph.harvard.edu ygrad@hsph.harvard.edu.ORCID 0000-0001-5646-1314
Marc Lipsitch *Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. mlipsitc@hsph.harvard.edu ygrad@hsph.harvard.edu.ORCID 0000-0003-1504-9213

Funding

Understanding and controlling antibiotic resistanceU54GM088558 · NIGMS · HARVARD SCHOOL OF PUBLIC HEALTH · PI LIPSITCH, MARC · 2009 to 2018
$26.4M
Epidemiology of Infectious Diseases and BiodefenseT32AI007535 · NIAID · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI GRAD, YONATAN H, MURRAY, MEGAN B · 1998 to 2025
$4.8M
NIAID NIH HHS T32 AI007535NIGMS NIH HHS U54 GM088558Wellcome Trust
6 · The paper itself

Abstract

It is urgent to understand the future of severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) transmission. We used estimates of seasonality, immunity, and cross-immunity for human coronavirus OC43 (HCoV-OC43) and HCoV-HKU1 using time-series data from the United States to inform a model of SARS-CoV-2 transmission. We projected that recurrent wintertime outbreaks of SARS-CoV-2 will probably occur after the initial, most severe pandemic wave. Absent other interventions, a key metric for the success of social distancing is whether critical care capacities are exceeded. To avoid this, prolonged or intermittent social distancing may be necessary into 2022. Additional interventions, including expanded critical care capacity and an effective therapeutic, would improve the success of intermittent distancing and hasten the acquisition of herd immunity. Longitudinal serological studies are urgently needed to determine the extent and duration of immunity to SARS-CoV-2. Even in the event of apparent elimination, SARS-CoV-2 surveillance should be maintained because a resurgence in contagion could be possible as late as 2024.

Indexed as

Models, BiologicalBetacoronavirusCoronavirus InfectionsCoronavirus OC43, HumanCOVID-19Disease OutbreaksDisease Transmission, InfectiousHumansPandemicsPneumonia, ViralSARS-CoV-2Seasons

Identifiers

PMID32291278
PMCPMC7164482

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.