Evidence map›Paper›PMID 32291273›Full record

ArticleDevelopment (Cambridge, England)2020

NF-κB signaling regulates the formation of proliferating Müller glia-derived progenitor cells in the avian retina.

Isabella Palazzo, Kyle Deistler, Thanh V Hoang, Seth Blackshaw, Andy J Fischer

Open access · greenAbstract read
In one paragraph

Article in Development (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. The neuroimmune interface in retinal regeneration.Progress in retinal and eye research · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Monocyte Invasion into the Retina Restricts the Regeneration of Neurons from Müller Glia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Ocular Vascular Diseases: From Retinal Immune Privilege to Inflammation.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Isabella PalazzoDepartment of Neuroscience, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-5752-0969
Kyle DeistlerDepartment of Neuroscience, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.
Thanh V HoangSolomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Seth BlackshawSolomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0002-1338-8476
Andy J FischerDepartment of Neuroscience, College of Medicine, The Ohio State University, Columbus, OH 43210, USA andrew.fischer@osumc.edu.ORCID 0000-0001-6123-7405
The Ohio State University · USJohns Hopkins University · US

Funding

Transcriptional regulation of retinal cell differentiation and functionR01EY020560 · NEI · JOHNS HOPKINS UNIVERSITY · PI BLACKSHAW, SETH · 2011 to 2021
$4.4M
Muller glia: roles in retinal homeostasis and neuronal regenerationR01EY022030 · NEI · OHIO STATE UNIVERSITY · PI FISCHER, ANDY J · 2012 to 2021
$3.5M
Comparative transcriptomic and epigenomic analyses of Muller glia reprogrammingU01EY027267 · NEI · UNIVERSITY OF NOTRE DAME · PI BLACKSHAW, SETH, HYDE, DAVID R · 2016 to 2019
$3.0M
Identification of gene regulatory networks that control proliferative and neurogenic competence in mammalian Müller gliaR01EY031685 · NEI · JOHNS HOPKINS UNIVERSITY · PI BLACKSHAW, SETH · 2020 to 2023
$2.0M
NEI NIH HHS R01 EY020560NEI NIH HHS R01 EY022030NEI NIH HHS R01 EY031685NEI NIH HHS U01 EY027267
6 · The paper itself

Abstract

Retinal regeneration is robust in some cold-blooded vertebrates, but this process is ineffective in warm-blooded vertebrates. Understanding the mechanisms that suppress the reprogramming of Müller glia into neurogenic progenitors is key to harnessing the regenerative potential of the retina

Indexed as

AnimalsCell ProliferationCellular ReprogrammingChickensEpendymoglial CellsGene SilencingIntercellular Signaling Peptides and ProteinsMicrogliaNerve RegenerationNeurogenesisNF-kappa BRetinaSignal TransductionStem CellsSulfasalazineIntercellular Signaling Peptides and ProteinsNF-kappa BSulfasalazineGliaMüller gliaNF-κBRegenerationRetina

Identifiers

PMID32291273
PMCPMC7325431
OpenAlexW3015329658

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.