Evidence map›Paper›PMID 32290615›Full record

ArticleInternational journal of molecular sciences2020

Expression of a Constitutively Active Form of

Viviane K S Kawata Matsuura, Carolina Andrea Yoshida, Hisato Komori, Chiharu Sakane, Kei Yamana, Qing Jiang, Toshihisa Komori

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Tyrosine Kinase Src Is a Regulatory Factor of Bone Homeostasis.International journal of molecular sciences · 2022
    Review
  5. Article
  6. Molecular Processes in Chondrocyte Biology.International journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Viviane K S Kawata MatsuuraBasic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Carolina Andrea YoshidaBasic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Hisato KomoriBasic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Chiharu SakaneDivision of Comparative Medicine, Life Science Support Center, Nagasaki University, Nagasaki 852-8523, Japan.
Kei YamanaTeijin Institute for Bio-Medical Research, TEIJIN LIMITED, Tokyo 100-8585, Japan.
Qing JiangBasic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Toshihisa KomoriBasic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Nagasaki University · JPTeijin (Japan) · JP

Funding

Japanese Ministry of Education, Culture, Sports, Science and Technology 18H05283Japanese Ministry of Education, Culture, Sports, Science and Technology 18K17017Japanese Ministry of Education, Culture, Sports, Science and Technology 19K18946
6 · The paper itself

Abstract

Runx2 is required for chondrocyte proliferation and maturation. In the search of Runx2 target genes in chondrocytes, we found that Runx2 up-regulated the expression of hematopoietic cell kinase (

Indexed as

AnimalsApoptosisCell ProliferationCells, CulturedChondrocytesCore Binding Factor Alpha 1 SubunitHedgehog ProteinsMiceMice, Inbred C57BLMice, TransgenicProto-Oncogene Proteins c-hckSignal TransductionWnt Signaling PathwayCore Binding Factor Alpha 1 SubunitHck protein, mouseHedgehog ProteinsProto-Oncogene Proteins c-hckchondrocyte proliferationHckhedgehogRunx2Wnt

Identifiers

PMID32290615
PMCPMC7215647
OpenAlexW3016005642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.