Evidence map›Paper›PMID 32290576›Full record

ArticleJournal of clinical medicine2020

Association of Sedentary Behavior with Brain Structure and Intelligence in Children with Overweight or Obesity: The ActiveBrains Project.

Juan Pablo Zavala-Crichton, Irene Esteban-Cornejo, Patricio Solis-Urra, José Mora-Gonzalez, Cristina Cadenas-Sanchez, María Rodriguez-Ayllon, Jairo H Migueles, Pablo Molina-Garcia, Juan Verdejo-Roman, Arthur F Kramer and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02295072 (ActiveBrains), which is not on this map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02295072 nacompletednot on this map

ActiveBrains: Effects of an Exercise-based Randomized Controlled Trial on Cognition, Brain Structure and Brain Function in Overweight/Obese Preadolescent Children

TypeinterventionalSponsorUniversidad de GranadaRan2014 to 2017Enrolled110ConditionsCognitive Function 1, Social, Mental Health Wellness 1, Obesity, OverweightArmsA 5-months physical exercise-based program
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  13. Sedentary behavior and lifespan brain health.Trends in cognitive sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Juan Pablo Zavala-CrichtonPROFITH "PROmoting FITness and Health Through Physical Activity" Research Group, Sport and Health University Research Institute (iMUDS), Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, 18071 Granada, Spain.ORCID 0000-0002-0727-4456
Irene Esteban-CornejoPROFITH "PROmoting FITness and Health Through Physical Activity" Research Group, Sport and Health University Research Institute (iMUDS), Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, 18071 Granada, Spain.ORCID 0000-0002-0027-1770
Patricio Solis-UrraPROFITH "PROmoting FITness and Health Through Physical Activity" Research Group, Sport and Health University Research Institute (iMUDS), Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, 18071 Granada, Spain.ORCID 0000-0002-2493-9528
José Mora-GonzalezPROFITH "PROmoting FITness and Health Through Physical Activity" Research Group, Sport and Health University Research Institute (iMUDS), Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, 18071 Granada, Spain.ORCID 0000-0003-2346-8776
Cristina Cadenas-SanchezPROFITH "PROmoting FITness and Health Through Physical Activity" Research Group, Sport and Health University Research Institute (iMUDS), Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, 18071 Granada, Spain.ORCID 0000-0002-4513-9108
María Rodriguez-AyllonPROFITH "PROmoting FITness and Health Through Physical Activity" Research Group, Sport and Health University Research Institute (iMUDS), Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, 18071 Granada, Spain.ORCID 0000-0002-8267-0440
Jairo H MiguelesPROFITH "PROmoting FITness and Health Through Physical Activity" Research Group, Sport and Health University Research Institute (iMUDS), Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, 18071 Granada, Spain.ORCID 0000-0003-0366-6935
Pablo Molina-GarciaPROFITH "PROmoting FITness and Health Through Physical Activity" Research Group, Sport and Health University Research Institute (iMUDS), Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, 18071 Granada, Spain.ORCID 0000-0001-6888-0997
Juan Verdejo-RomanMind, Brain and Behavior Research Center (CIMCYC), University of Granada, 18071 Granada, Spain.ORCID 0000-0001-5112-8918
Arthur F KramerDepartment of Psychology, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0001-5870-2724
Charles H HillmanDepartment of Psychology, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0002-3722-5612
Kirk I EricksonBrain Aging & Cognitive Health Lab, Department of Psychology, University of Pittsburgh, 3601 Sennott Square, Pittsburgh, PA 15218, USA.ORCID 0000-0001-8736-981X
Andrés CatenaDepartment of Experimental Psychology, Mind, Brain and Behavior Research Centre (CIMCYC), University of Granada, 18011 Granada, Spain.ORCID 0000-0002-0775-5751
Francisco B OrtegaPROFITH "PROmoting FITness and Health Through Physical Activity" Research Group, Sport and Health University Research Institute (iMUDS), Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, 18071 Granada, Spain.ORCID 0000-0003-2001-1121

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the associations of different sedentary behaviors (SB) with gray matter volume and we tested whether SB related to gray matter volume is associated with intelligence.

methods99 children with overweight or obesity aged 8-11 years participated in this cross-sectional study. SB was measured using the Youth Activity Profile-Spain questionnaire. T1-weighted images were acquired with a 3.0 T Magnetom Tim Trio system. Intelligence was assessed with the Kaufman Brief Test. Whole-brain voxel-wise multiple regression models were used to test the associations of each SB with gray matter volume.

resultsWatching TV was associated with lower gray matter volume in six brain regions (β ranging -0.314 to -0.489 and cluster size 106 to 323 voxels;

conclusionsSB could have the potential to negatively influence brain structure and, in turn, intelligence in children with overweight/obesity.

Indexed as

brainchildhoodcognitionKeywords: sedentarinessmagnetic resonance imagingobesityTV viewing

Identifiers

PMID32290576
PMCPMC7230478

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.