Evidence map›Paper›PMID 32290439›Full record

ArticleCancers2020

Genomic Profiling of Circulating Tumor DNA Predicts Outcome and Demonstrates Tumor Evolution in ALK-Positive Non-Small Cell Lung Cancer Patients.

Anne Tranberg Madsen, Anne Winther-Larsen, Tine McCulloch, Peter Meldgaard, Boe Sandahl Sorensen

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  11. Liquid Biopsy, ctDNA Diagnosis through NGS.Life (Basel, Switzerland) · 2021
    Review
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anne Tranberg MadsenDepartment of Clinical Biochemistry, Aarhus University Hospital, 8200 Aarhus N, Denmark.ORCID 0000-0001-9146-5943
Anne Winther-LarsenDepartment of Clinical Biochemistry, Aarhus University Hospital, 8200 Aarhus N, Denmark.
Tine McCullochDepartment of Oncology, Aalborg University Hospital, 9000 Aalborg, Denmark.
Peter MeldgaardDepartment of Oncology, Aarhus University Hospital, 8200 Aarhus N, Denmark.ORCID 0000-0002-5788-4463
Boe Sandahl SorensenDepartment of Clinical Biochemistry, Aarhus University Hospital, 8200 Aarhus N, Denmark.
Aarhus University Hospital · DKAalborg University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the rapid development of targeted therapies for the treatment of cancer, methods for predicting response and outcome are in high demand. Non-small cell lung cancer driven by genomic rearrangements of the anaplastic lymphoma kinase (

Indexed as

ALK tyrosine kinase receptorcell-free DNAcirculating tumor DNAnext-generation sequencingserial monitoringtargeted therapy

Identifiers

PMID32290439
PMCPMC7226192
OpenAlexW3016190832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.