Evidence map›Paper›PMID 32290271›Full record

Trial reportNutrients2020

Effects of Whey Protein Supplementation on Aortic Stiffness, Cerebral Blood Flow, and Cognitive Function in Community-Dwelling Older Adults: Findings from the ANCHORS A-WHEY Clinical Trial.

Wesley K Lefferts, Jacqueline A Augustine, Nicole L Spartano, William E Hughes, Matthew C Babcock, Brigid K Heenan, Kevin S Heffernan

Open access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Wesley K LeffertsHuman Performance Laboratory, Department of Exercise Science, Syracuse University, Syracuse, NY 13244, USA.ORCID 0000-0001-5957-391X
Jacqueline A AugustineHuman Performance Laboratory, Department of Exercise Science, Syracuse University, Syracuse, NY 13244, USA.
Nicole L SpartanoHuman Performance Laboratory, Department of Exercise Science, Syracuse University, Syracuse, NY 13244, USA.
William E HughesHuman Performance Laboratory, Department of Exercise Science, Syracuse University, Syracuse, NY 13244, USA.
Matthew C BabcockHuman Performance Laboratory, Department of Exercise Science, Syracuse University, Syracuse, NY 13244, USA.
Brigid K HeenanHuman Performance Laboratory, Department of Exercise Science, Syracuse University, Syracuse, NY 13244, USA.
Kevin S HeffernanHuman Performance Laboratory, Department of Exercise Science, Syracuse University, Syracuse, NY 13244, USA.
Syracuse University · US

Funding

Precision Lifestyle Medicine and Translation Research (PREMIER)T32HL134634 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI RACHEL CASKEY, Jun Ma · 2018 to 2026
$2.4M
Dairy Management Dairy Research Institute 1154NHLBI NIH HHS T32 HL134634NIH HHS P30 AG0344645NOW supplements Donated whey protein isolate and carbohydrate (Carbogain)
6 · The paper itself

Abstract

ANCHORS A-WHEY was a 12-week randomized controlled trial (RCT) designed to examine the effect of whey protein on large artery stiffness, cerebrovascular responses to cognitive activity and cognitive function in older adults.

methods99 older adults (mean ± SD; age 67 ± 6 years, BMI 27.2 ± 4.7kg/m

resultscfPWV increased slightly in CHO and significantly decreased in WPI (

conclusionsCompared to CHO, WPI supplementation results in favorable reductions in aortic stiffness and aortic hemodynamic load with limited effects on cognitive function and cerebrovascular function in community-dwelling older adults.

Indexed as

Cerebrovascular CirculationCognitionDietary SupplementsElasticityHemodynamicsIndependent LivingAgedAge FactorsAortaDietary CarbohydratesFemaleHumansMaleMiddle AgedNutritional Physiological PhenomenaWhey ProteinsDietary CarbohydratesWhey Proteinsblood pressureolder adultsvascular stiffnesswhey protein isolate

Identifiers

PMID32290271
PMCPMC7230701
OpenAlexW3015914717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.