Evidence map›Paper›PMID 32290254›Full record

ReviewJournal of clinical medicine2020

Sarcoidosis: Causes, Diagnosis, Clinical Features, and Treatments.

Rashi Jain, Dhananjay Yadav, Nidhi Puranik, Randeep Guleria, Jun-O Jin

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 2 pooled it
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 2 syntheses or guidelines pooled it, 171 citations in OpenAlex.

  1. Pooled it
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  4. Observational
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  9. Review
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  11. Article
  12. Metabolomic signaling in sarcoidosis pathogenesis.Current opinion in immunology · 2026
    Review
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  14. Article
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34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Rashi JainDepartment of Pulmonary Critical Care and Sleep Medicine, AIIMS, New Delhi 110029, India.ORCID 0000-0002-5406-8196
Dhananjay YadavDepartment of Medical Biotechnology, Yeungnam University, Gyeongsan 712-749, Korea.ORCID 0000-0003-4047-7236
Nidhi PuranikDepartment of Biological Science, Bharathiar University, Coimbatore, Tamil Nadu-641046, India.
Randeep GuleriaDepartment of Pulmonary Critical Care and Sleep Medicine, AIIMS, New Delhi 110029, India.
Jun-O JinDepartment of Medical Biotechnology, Yeungnam University, Gyeongsan 712-749, Korea.ORCID 0000-0003-4216-8111
All India Institute of Medical Sciences Raipur · INBharathiar University · INShanghai Public Health Clinical Center · CNYeungnam University · KR

Funding

13th Five-Year National Major Science and Technology Project on Discovery of New Drugs: Construction of Technology Platform for Clinical Evaluation on Anti-HIV Drugs 2017ZX09304027National Research Foundation of Korea NRF-2019R1G1A1008566
6 · The paper itself

Abstract

Sarcoidosis is a multisystem granulomatous disease with nonspecific clinical manifestations that commonly affects the pulmonary system and other organs including the eyes, skin, liver, spleen, and lymph nodes. Sarcoidosis usually presents with persistent dry cough, eye and skin manifestations, weight loss, fatigue, night sweats, and erythema nodosum. Sarcoidosis is not influenced by sex or age, although it is more common in adults (< 50 years) of African-American or Scandinavians decent. Diagnosis can be difficult because of nonspecific symptoms and can only be verified following histopathological examination. Various factors, including infection, genetic predisposition, and environmental factors, are involved in the pathology of sarcoidosis. Exposures to insecticides, herbicides, bioaerosols, and agricultural employment are also associated with an increased risk for sarcoidosis. Due to its unknown etiology, early diagnosis and detection are difficult; however, the advent of advanced technologies, such as endobronchial ultrasound-guided biopsy, high-resolution computed tomography, magnetic resonance imaging, and 18F-fluorodeoxyglucose positron emission tomography has improved our ability to reliably diagnose this condition and accurately forecast its prognosis. This review discusses the causes and clinical features of sarcoidosis, and the improvements made in its prognosis, therapeutic management, and the recent discovery of potential biomarkers associated with the diagnostic assay used for sarcoidosis confirmation.

Indexed as

biomarkerscausediagnosismanagementsarcoidosis

Identifiers

PMID32290254
PMCPMC7230978
OpenAlexW3015922762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.