Evidence map›Paper›PMID 32290196›Full record

ReviewMolecules (Basel, Switzerland)2020

Targeted Radionuclide Therapy of Prostate Cancer-From Basic Research to Clinical Perspectives.

Malwina Czerwińska, Aleksander Bilewicz, Marcin Kruszewski, Aneta Wegierek-Ciuk, Anna Lankoff

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 105 citations in OpenAlex.

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  8. Evaluation ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
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  14. Optimized Production ofNuclear medicine and molecular imaging · 2024
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  19. Immunological effects of radiopharmaceutical therapy.Frontiers in nuclear medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Malwina CzerwińskaCentre for Radiobiology and Biological Dosimetry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland.
Aleksander BilewiczCentre of Radiochemistry and Nuclear Chemistry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland.ORCID 0000-0003-2490-3303
Marcin KruszewskiCentre for Radiobiology and Biological Dosimetry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland.ORCID 0000-0003-4554-8566
Aneta Wegierek-CiukDepartment of Medical Biology, Institute of Biology, Jan Kochanowski University, Uniwersytecka 7, 24-406 Kielce, Poland.
Anna LankoffCentre for Radiobiology and Biological Dosimetry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland.ORCID 0000-0002-6661-7949
Instytut Chemii i Techniki Jądrowej · PLJan Kochanowski University · PL

Funding

Narodowe Centrum Nauki OPUS10-UMO 2015/19/B/NZ7/02166
6 · The paper itself

Abstract

Prostate cancer is the most commonly diagnosed malignancy in men and the second leading cause of cancer-related deaths in Western civilization. Although localized prostate cancer can be treated effectively in different ways, almost all patients progress to the incurable metastatic castration-resistant prostate cancer. Due to the significant mortality and morbidity rate associated with the progression of this disease, there is an urgent need for new and targeted treatments. In this review, we summarize the recent advances in research on identification of prostate tissue-specific antigens for targeted therapy, generation of highly specific and selective molecules targeting these antigens, availability of therapeutic radionuclides for widespread medical applications, and recent achievements in the development of new-generation small-molecule inhibitors and antibody-based strategies for targeted prostate cancer therapy with alpha-, beta-, and Auger electron-emitting radionuclides.

Indexed as

Molecular Targeted TherapyRadioisotopesRadiopharmaceuticalsAnimalsBiomarkers, TumorDrug DevelopmentHumansImmunoconjugatesLigandsMaleNanoparticlesProstatic NeoplasmsTheranostic NanomedicineBiomarkers, TumorImmunoconjugatesLigandsRadioisotopesRadiopharmaceuticalsprostate cell-surface receptorsprostate targeted therapyPSMA ligandsPSMA-targeted radioimmunoconjugates

Identifiers

PMID32290196
PMCPMC7181060
OpenAlexW3015310737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.