ReviewBrain sciences2020
Metronidazole Encephalopathy EEG Features: A Case Report with Systematic Review of the Literature.
Review in Brain sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Reversible Metronidazole-Induced Encephalopathy With Typical MRI Features Following a Low Cumulative Dose: Case Report.Clinical medicine insights. Case reports · 2026Article
- Cost-Effective Nanosensor Solutions for Ultra-Sensitive Detection of Metronidazole.Analytical science advances · 2025Review
- Development of cefepime-induced encephalopathy in a patient with depression and rectal cancer: A case report.Neuropsychopharmacology reports · 2025Article
- Diffuse subcortical white matter restriction: An uncommon finding on metronidazole toxicity.The neuroradiology journal · 2023Article
- Electroencephalography as a diagnostic tool for late-onset efavirenz neurotoxicity syndrome.PloS one · 2023Article
- Metronidazole-induced reversible cerebellar dysfunction.BMJ case reports · 2021Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metronidazole-induced encephalopathy (MIE) is a rare and often under-recognized iatrogenic condition. The diagnosis should be considered in metronidazole-treated patients presenting with acute encephalopathy, unprovoked seizures and cerebellar signs. While typical magnetic resonance imaging (MRI) findings strongly support the diagnosis, electroencephalography (EEG) features have been rarely reported and poorly described. We present a longitudinal EEG assessment in one patient with encephalopathy due to metronidazole toxicity who presented a peculiar EEG pattern presentation and evolution. During the acute phase of encephalopathy, the EEG showed a monomorphic, sharply contoured theta activity symmetrically represented over frontal regions with an anterior-posterior progression which evolved in parallel with clinical worsening. Together with a systematic review of the literature, we discuss whether this EEG activity may represent a distinct neurophysiological correlate of 'cerebellar encephalopathy'.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.