Evidence map›Paper›PMID 32290067›Full record

ArticleAnimals : an open access journal from MDPI2020

Inflammasome Activation in Bovine Peripheral Blood-Derived Macrophages Is Associated with Actin Rearrangement.

Amin Tahoun, Kirsty Jensen, Hanem El-Sharkawy, David Gally, Amira M Rizk, Jamaan Ajarem, Ahmed Allam, Ayman M Mahmoud

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Amin TahounDivision of Immunity and Infection, The Roslin Institute and R(D)SVS, The University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.
Kirsty JensenDivision of Immunity and Infection, The Roslin Institute and R(D)SVS, The University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.
Hanem El-SharkawyDepartment of Poultry and Rabbit Diseases, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh 33511, Egypt.
David GallyDivision of Immunity and Infection, The Roslin Institute and R(D)SVS, The University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.
Amira M RizkDepartment of Bacteriology, Mycology and Immunology, Faculty of Veterinary Medicine, Benha University, Benha 13511, Egypt.
Jamaan AjaremZoology Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Ahmed AllamZoology Department, Faculty of Science, Beni-Suef University, Beni-Suef 62514, Egypt.
Ayman M MahmoudZoology Department, Faculty of Science, Beni-Suef University, Beni-Suef 62514, Egypt.ORCID 0000-0003-0279-6500
Beni-Suef University · EGKafrelsheikh University · EGRoslin Institute · GBBenha University · EGKing Saud University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation is critical for infection control and acts as an arsenal defense mechanism against invading microbes through activation of the host immune system. It works via its inflammasome components to sense the dangerous invading microorganism and send messages to the immune system to destroy them. To date, the function of bovine macrophage inflammasome and its relationship with actin has not been identified. This study aimed to investigate the activation of bovine inflammasome by phase one flagellin from

Indexed as

actin rearrangementflagellated bacteriainflammasomesinflammationmacrophages

Identifiers

PMID32290067
PMCPMC7223366
OpenAlexW3015241390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.