Evidence map›Paper›PMID 32290064›Full record

ArticleCancers2020

Magnetic-Based Enrichment of Rare Cells from High Concentrated Blood Samples.

Junhao Wu, Katharina Raba, Rosa Guglielmi, Bianca Behrens, Guus Van Dalum, Georg Flügen, Andreas Koch, Suraj Patel, Wolfram T Knoefel, Nikolas H Stoecklein and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Junhao WuDepartment of General, Visceral and Pediatric Surgery, University Hospital and Medical Faculty of the Heinrich-Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.
Katharina RabaInstitute for Transplantation Diagnostics and Cell Therapeutics, University Hospital and Medical Faculty of the Heinrich-Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Rosa GuglielmiDepartment of General, Visceral and Pediatric Surgery, University Hospital and Medical Faculty of the Heinrich-Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.
Bianca BehrensDepartment of General, Visceral and Pediatric Surgery, University Hospital and Medical Faculty of the Heinrich-Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.
Guus Van DalumDepartment of General, Visceral and Pediatric Surgery, University Hospital and Medical Faculty of the Heinrich-Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.
Georg FlügenDepartment of General, Visceral and Pediatric Surgery, University Hospital and Medical Faculty of the Heinrich-Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.ORCID 0000-0002-9322-1659
Andreas KochThermo Fisher Scientific, Postfach 200152, Frankfurter Str. 129B, 64293 Darmstadt, Germany.
Suraj PatelThermo Fisher Scientific, 3 Fountain Drive, Inchinnan, Renfrew PA4 9RF, UK.ORCID 0000-0003-1101-382X
Wolfram T KnoefelDepartment of General, Visceral and Pediatric Surgery, University Hospital and Medical Faculty of the Heinrich-Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.
Nikolas H StoeckleinDepartment of General, Visceral and Pediatric Surgery, University Hospital and Medical Faculty of the Heinrich-Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.ORCID 0000-0002-3412-594X
Rui P L NevesDepartment of General, Visceral and Pediatric Surgery, University Hospital and Medical Faculty of the Heinrich-Heine University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany.
Düsseldorf University Hospital · DEThermo Fisher Scientific (Germany) · DEThermo Fisher Scientific (United Kingdom) · GB

Funding

Brigitte und Dr. Konstanze Wegener Foundation Project #01 to N.H.S. and W.T.K.Innovative Medicines Initiative in conjunction with CANCER-ID [Grant Agreement #115749 to N.H.S.]
6 · The paper itself

Abstract

Here, we tested two magnetic-bead based systems for the enrichment and detection of rare tumor cells in concentrated blood products. For that, the defined numbers of cells from three pancreatic cancer cell lines were spiked in 10

Indexed as

circulating tumor cellsconcentrated blood productsdiagnostic leukapheresisimmunomagnetic enrichmentIsoFluxKingFisher

Identifiers

PMID32290064
PMCPMC7225976
OpenAlexW3015709037

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.