Evidence map›Paper›PMID 32289747›Full record

ArticleJournal of anxiety disorders2020

Overcontrol and neural response to errors in pediatric anxiety disorders.

Kirsten Gilbert, Michael T Perino, Michael J Myers, Chad M Sylvester

Open access · greenAbstract read
In one paragraph

Article in Journal of anxiety disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

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  15. Associations of observed preschool performance monitoring with brain functional connectivity in adolescence.Cortex; a journal devoted to the study of the nervous system and behavior · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kirsten GilbertDepartment of Psychiatry, Washington University in St. Louis, 4444 Forest Park, Suite 2100, St. Louis MO, 63108, USA. Electronic address: gilbertk@wustl.edu.
Michael T PerinoDepartment of Psychiatry, Washington University in St. Louis, 4444 Forest Park, Suite 2100, St. Louis MO, 63108, USA.
Michael J MyersDepartment of Psychiatry, Washington University in St. Louis, 4444 Forest Park, Suite 2100, St. Louis MO, 63108, USA.
Chad M SylvesterDepartment of Psychiatry, Washington University in St. Louis, 4444 Forest Park, Suite 2100, St. Louis MO, 63108, USA.
Washington University in St. Louis · US

Funding

Developmental Neuroscience and Child PsychopathologyT32MH100019 · NIMH · WASHINGTON UNIVERSITY · PI Deanna Barch, JOAN L. LUBY · 2013 to 2026
$4.8M
ATTENTION AND RELATED FUNCTIONAL BRAIN NETWORKS IN PEDIATRIC ANXIETY DISORDERSK23MH109983 · NIMH · WASHINGTON UNIVERSITY · PI SYLVESTER, CHAD MICHAEL · 2016 to 2020
$1.1M
Heightened Performance Monitoring and Overcontrol: Neural Markers and Caregiving Processes in Developmental Risk TrajectoriesK23MH115074 · NIMH · WASHINGTON UNIVERSITY · PI GILBERT, KIRSTEN · 2017 to 2021
$821k
NIMH NIH HHS K23 MH109983NIMH NIH HHS K23 MH115074NIMH NIH HHS T32 MH100019
6 · The paper itself

Abstract

Multiple risk factors that may contribute to the development and severity of pediatric anxiety disorders, one of which is dimensional overcontrol. Overcontrol is a constellation of characteristics including heightened performance monitoring, inflexibility, perfectionism and aversion to making mistakes. In this study, we examined overcontrol in children with anxiety disorders and tested whether the underlying dimension of overcontrol specifically explains altered brain response to errors in pediatric anxiety disorders. Parent-reported scores of child overcontrol were collected in a sample of children (ages 8-12 years) with (n = 35) and without (n = 34) anxiety disorders and the relationship of overcontrol and anxiety symptoms to neural responding to errors during functional magnetic resonance imaging (fMRI) was examined. Results indicated childhood overcontrol was elevated in pediatric anxiety disorders and was significantly associated with anxiety severity, even when controlling for comorbid depression and ADHD. Additionally, overcontrol was associated with reduced neural response to errors versus correct responses in the bilateral dorsal anterior cingulate cortex (dACC) and insula, even when controlling for anxiety symptoms. Overcontrol may serve as an underlying mechanism associated with clinical pediatric anxiety that demonstrates significant associations with aberrant neural error responding. Overcontrol may be an underlying mechanism contributing to pediatric anxiety that could be targeted for early intervention.

Indexed as

PerfectionismAnxietyAnxiety DisordersAttention Deficit Disorder with HyperactivityBrainCerebral CortexChildDepressionFemaleHumansMagnetic Resonance ImagingMaleNeuronsParentsdACCErrorsOvercontrolPediatric anxietyPerformance monitoring

Identifiers

PMID32289747
PMCPMC7260107
OpenAlexW3015779420

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.