Evidence map›Paper›PMID 32289045›Full record

ArticleAnales de pediatria2019

Previous or coincident infections with suspected Kawasaki disease. Should we change our approach?

Elisa Fernández-Cooke, Ana Barrios Tascón, Jordi Antón-López, Carlos Daniel Grasa Lozano, Judith Sánchez-Manubens, Cristina Calvo, Working Group for the Study of Kawasaki Disease (KAWA-RACE)

Open access · diamondAbstract read
In one paragraph

Article in Anales de pediatria, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Elisa Fernández-CookeServicio de Pediatría, Hospital 12 de Octubre, Madrid, Spain.
Ana Barrios TascónServicio de Pediatría, Hospital Infanta Sofía, San Sebastián de los Reyes (Madrid), Spain.
Jordi Antón-LópezServicio de Pediatría, Hospital Sant Joan de Déu, Esplugues de Llobregat (Barcelona), Spain.
Carlos Daniel Grasa LozanoServicio de Pediatría, Hospital 12 de Octubre, Madrid, Spain.
Judith Sánchez-ManubensServicio de Pediatría, Hospital Sant Joan de Déu, Esplugues de Llobregat (Barcelona), Spain.
Cristina CalvoServicio de Pediatría, Hospital Universitario La Paz, Madrid, Spain.
Working Group for the Study of Kawasaki Disease (KAWA-RACE)
Hospital Sant Joan de Déu Barcelona · ESHospital Universitario 12 De Octubre · ESHospital Universitario Infanta Sofía · ESHospital Universitario La Paz · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionKawasaki disease (KD) is a multisystem vasculitis associated with coronary artery abnormalities. Infections could be a trigger of the inflammation. The main aim of this study was to describe the presence of infections in children with KD, and to analyse the clinical characteristics and the presence of coronary abnormalities in these cases. PATIENTS AND

methodsA retrospective study was performed within the Kawasaki Disease network (KAWA-RACE (2011-2016). An analysis was performed that included patients with positive microbiological findings (PMF) during the acute phase, as well as those with a previous recent infection (PRI) during the 4 weeks preceding KD diagnosis.

resultsThe study included a total of 621 children with KD, with PMF being found in 101 (16.3%) patients, and a PRI in 107 (17.2%). Significantly less echocardiographic abnormalities were found in the group with a PRI, when compared to those without a PRI (23 vs. 35%,

conclusionsIn the present study, no differences were found in the incidence of coronary aneurysms in either of the groups, with or without PRI or PMF. Therefore, if KD is suspected, appropriate treatment should be started despite having a confirmed infection.

Indexed as

Coronary aneurysmKawasaki diseaseVasculitis

Identifiers

PMID32289045
PMCPMC7146762
OpenAlexW2921036776

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.