ReviewProgress in polymer science2017
Quaternary ammonium-based biomedical materials: State-of-the-art, toxicological aspects and antimicrobial resistance.
Review in Progress in polymer science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 186 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
186 citing papers in PubMed, 614 citations in OpenAlex.
- The evolution of click chemistry: from classical reactions to next-generation platforms.RSC advances · 2026Review
- A New Sustainable Approach to Antibiotic Resistance: Development of bis-Quaternary Ammonium Salts From 2,4,6-Trichloro-1,3,5-Triazine.ChemMedChem · 2026Article
- Development of Antimicrobial Coatings by Incorporating Curcumin and Silver-Based Additive into a Commercial Water-Based Paint.Biomimetics (Basel, Switzerland) · 2026Article
- Aza-Michael Quaternization: Addition of Tertiary Amines to Allenic Michael Acceptors Furnishes Quaternary Ammonium Compounds.JACS Au · 2026Article
- Polyethyleneimine-protoporphyrin IX and its Zn(II) complex conjugates for photodynamic inactivation of Staphylococcus aureus on cucumber mesocarp surfaces.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026Article
- Synergistic control of viral persistence via wettability and ion release on antiviral coatings.Materials today. Bio · 2026Article
- Novel Antimicrobial Composites Modified with Nanosilver, CuSOMaterials (Basel, Switzerland) · 2026Article
- Emergence, evolution, and global dissemination of antimicrobial resistance: A One Health review.Archives of microbiology · 2026Review
- Investigation Into the Variations in the Interactions Between Different Selenium Sources and Gut Microbiota.Food science & nutrition · 2026Article
- The Role of Matrix Metalloproteinases in Orthodontics, Dental Trauma, Restorative Dentistry, and Endodontics: Molecular Mechanisms and Clinical Implications.International journal of molecular sciences · 2026Review
- Photoinduced Inactivation of Pathogenic Microorganisms via Cotton Textile Functionalized with a Novel Iodinated BODIPY Derivative.Molecules (Basel, Switzerland) · 2026Article
- A multi-modal strategy for enhancing titanium-bone interface strength and antimicrobial properties of PMMA bone cements.Materials & design · 2026Article
- Syntheses, DNA interactions, and photodynamic antimicrobial properties of near-infrared indolium carbocyanine dyes.RSC advances · 2026Article
- When Disinfection Fails: Biocide Tolerance as a Driver ofAntibiotics (Basel, Switzerland) · 2026Review
- Mechanism and Molecular Design Principles of Cationic Surfactants: From Charge-Driven Membrane Interactions to Next-Generation Quaternary Ammonium Compounds.ChemMedChem · 2026Review
- Antimicrobial Materials Used in Coating Dental Implant Surfaces: State of the Art and Future Prospectives.Materials (Basel, Switzerland) · 2026Review
- Nanomedicine applications for the treatment of Staphylococcus aureus infections.FEMS microbiology reviews · 2026Review
- Injectable Deep Eutectic Solvent-Based Ionic Gel With Rapid Gelation and Broad Hemostatic Functionality.Advanced healthcare materials · 2026Article
- A "Detachable Polyanionic Protective Shell" Enveloping Photodynamic Cationic Nanoassemblies for Keratitis Treatment.Research (Washington, D.C.) · 2026Article
- Effect of Immersion in Quaternary Ammonium Methacryloxy Silane Mixed Monomer on the Mechanical Properties and Antibacterial Activity of a 3D-Printed Urethane Dimethacrylate Denture Base Resin.Journal of functional biomaterials · 2025Article
126 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Microbial infections affect humans worldwide. Many quaternary ammonium compounds have been synthesized that are not only antibacterial, but also possess antifungal, antiviral and anti-matrix metalloproteinase capabilities. Incorporation of quaternary ammonium moieties into polymers represents one of the most promising strategies for preparation of antimicrobial biomaterials. Various polymerization techniques have been employed to prepare antimicrobial surfaces with quaternary ammonium functionalities; in particular, syntheses involving controlled radical polymerization techniques enable precise control over macromolecular structure, order and functionality. Although recent publications report exciting advances in the biomedical field, some of these technological developments have also been accompanied by potential toxicological and antimicrobial resistance challenges. Recent evidenced-based data on the biomedical applications of antimicrobial quaternary ammonium-containing biomaterials that are based on randomized human clinical trials, the golden standard in contemporary medicinal science, are included in the present review. This should help increase visibility, stimulate debates and spur conversations within a wider scientific community on the implications and plausibility for future developments of quaternary ammonium-based antimicrobial biomaterials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.