ArticlePLoS neglected tropical diseases2020
The estimated burden of scrub typhus in Thailand from national surveillance data (2003-2018).
Article in PLoS neglected tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 61 citations in OpenAlex.
- Intravenous Doxycycline, Azithromycin, or Both for Severe Scrub Typhus.The New England journal of medicine · 2023Trial
- Clinical and Laboratory Features of Scrub Typhus among Adult Patients with Acute Febrile Illness in Tak and Nakhon Phanom Provinces, Thailand, 2017-2020.The American journal of tropical medicine and hygiene · 2026Article
- Korat-Scrub Typhus Score: A Clinical Tool for Predicting Scrub Typhus in Patients With Acute Undifferentiated Febrile Illness.Tropical medicine & international health : TM & IH · 2026Article
- Spatiotemporal prediction of scrub typhus incidence and environmental risk factors in Republic of Korea: a Bayesian hierarchical approach.Infectious diseases of poverty · 2026Article
- Neglected rickettsial diseases in Southeast Asia: Twenty-five years of progress in surveillance, diagnostics, and clinical research.PLoS neglected tropical diseases · 2026Review
- Environmental Conditions and Mite Vectors Shape the Spatiotemporal Patterns of Scrub Typhus in Guangdong Province, Mainland China.Tropical medicine and infectious disease · 2025Article
- Estimating scrub typhus and murine typhus incidence among adolescents and adults in Yangon, Myanmar.Tropical medicine & international health : TM & IH · 2025Article
- Scrub typhus in Nan province (Thailand): Seventeen years of data to understand the impact of land cover change.PLoS neglected tropical diseases · 2025Article
- Risk factors for scrub typhus infection in South India: population-based cohort study.Epidemiology and infection · 2025Observational
- Environmental change increases the transmission risk of visceral leishmaniasis in central China around the Taihang mountains.Environmental health : a global access science source · 2025Article
- Mathematical analysis of scrub typhus seasonal infection with re-scaled transmission rate considering Northeast India reported data from 2010 to 2022.Scientific reports · 2025Article
- The economic burden of scrub typhus disease among the tribal ethnic groups (Mizo) of Mizoram State, Northeast India.BMC public health · 2025Article
- Epidemiological Changes in Acute Febrile Diseases after the COVID-19 Pandemic in Thailand.The American journal of tropical medicine and hygiene · 2025Article
- Rickettsiosis Infections in Sarawak: Epidemiological Insights and Public Health Strategies.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025Review
- Retrospective analysis of spatiotemporal variation of scrub typhus in Yunnan Province, 2006-2022.PLoS neglected tropical diseases · 2024Article
- Community engagement around scrub typhus in northern Thailand: a pilot project.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2024Article
- Scrub typhus strikes: Menacing maternal and fetal health.Journal of family medicine and primary care · 2024Article
- Intraspecific sensilla dimorphism inHeliyon · 2024Article
- Identification of Bacteria and Viruses Associated with Patients with Acute Febrile Illness in Khon Kaen Province, Thailand.Viruses · 2024Article
- Exploring the effects and interactions of meteorological factors on the incidence of scrub typhus in Ganzhou City, 2008-2021.BMC public health · 2024Article
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Authors and funding
8 authors at 4 institutions in 4 countries.
Funding
Abstract
backgroundScrub typhus is a major cause of acute febrile illness in the tropics and is endemic over large areas of the Asia Pacific region. The national and global burden of scrub typhus remains unclear due to limited data and difficulties surrounding diagnosis. METHODOLOGY/PRINCIPAL
findingsScrub typhus reporting data from 2003-2018 were collected from the Thai national disease surveillance system. Additional information including the district, sub-district and village of residence, population, geographical, meteorological and satellite imagery data were also collected for Chiangrai, the province with the highest number of reported cases from 2003-2018. From 2003-2018, 103,345 cases of scrub typhus were reported with the number of reported cases increasing substantially over the observed period. There were more men than women, with agricultural workers the main occupational group affected. The majority of cases occurred in the 15-64 year old age group (72,144/99,543, 72%). Disease burden was greatest in the northern region, accounting for 53% of the total reported cases per year (mean). In the northern region, five provinces-Chiangrai, Chiangmai, Tak, Nan and Mae Hong Son-accounted for 84% (46,927/55,872) of the total cases from the northern region or 45% (46,927/103,345) of cases nationally. The majority of cases occurred from June to November but seasonality was less marked in the southern region. In Chiangrai province, elevation, rainfall, temperature, population size, habitat complexity and diversity of land cover contributed to scrub typhus incidence.
interpretationThe burden of scrub typhus in Thailand is high with disease incidence rising significantly over the last two decades. However, disease burden is not uniform with northern provinces particularly affected. Agricultural activity along with geographical, meteorological and land cover factors are likely to contribute to disease incidence. Our report, along with existing epidemiological data, suggests that scrub typhus is the most clinically important rickettsial disease globally.
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