Trial reportPloS one2020
Occupational exposure to HIV among nurses at a major tertiary hospital: Reporting and utilization of post-exposure prophylaxis; A cross-sectional study in the Western Cape, South Africa.
Trial report in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Healthcare-Associated Infection Causes and Mitigation Strategies:Saudi medical journal · 2026Pooled it
- Instruments for Assessing Population Knowledge of Pre-exposure Prophylaxis (PrEP) and/or Post-exposure Prophylaxis (PEP) for HIV: A Scoping Review.AIDS and behavior · 2026Article
- Healthcare providers' knowledge, attitude, and practice regarding occupational exposure to human papillomaviruses.BMC medical education · 2025Article
- Study of the risk assessment of nursing occupational exposure to major public health emergencies based on the Likelihood Exposure Consequence method.Journal of occupational health · 2025Article
- Occupational post-exposure prophylaxis among healthcare workers: a scoping review of factors affecting optimal utilization.Journal of the International AIDS Society · 2024Article
- Occupational exposure to HIV and utilization of post-exposure prophylaxis among healthcare workers at St. Peter's specialized hospital in Addis Ababa, Ethiopia.Scientific reports · 2023Article
- Healthcare Professionals' Practice of HIV Post-Exposure Prophylaxis in Clinical Settings in Karachi, Pakistan.Healthcare (Basel, Switzerland) · 2022Article
- HIV Knowledge and Stigmatizing Attitude towards People Living with HIV/AIDS among Medical Students in Jordan.International journal of environmental research and public health · 2022Article
- Prevalence of Occupational Exposure to HIV and Factors Associated with Compliance with Post-Exposure Prophylaxis Among Health Workers of the Biyem-Assi, Buea, and Limbe Health Districts of Cameroon Maternal and Child Health and AIDS.International journal of MCH and AIDS · 2022Article
- Healthcare practitioners and students' PEP knowledge, attitude and adherence in Southern Africa.Health SA = SA Gesondheid · 2022Article
- Assessment of mental health outcomes and associated factors among workers in community-based HIV care centers in the early stage of the COVID-19 outbreak in Mali.Health policy OPEN · 2020Article
- Patterns of Occupational Exposure to Human Immunodeficiency Virus and Post-Exposure Prophylaxis Among Health Care Personnel in a Tertiary Care Institute in South India - A Retrospective Case Series.Indian dermatology online journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhile treatment for HIV has greatly improved patient outcomes, health care workers, including nurses, remain at high risk of occupational exposure. The risk of exposure is a continuous concern in the South African health system that is overburdened by multiple stressors, including the highest HIV caseload in the world. The aim of this study was to estimate the prevalence of occupational exposure to HIV, reporting and utilization of post-exposure prophylaxis, knowledge, attitudes towards HIV post-exposure prophylaxis and infection control practices amongst nurses at a tertiary hospital in the Western Cape, South Africa.
methodsA cross-sectional study was conducted at Tygerberg hospital from the 4th to the 16th February 2019. Participants were front line nurses working in randomly selected wards. A self-administered questionnaire was used to collect data from participants.
resultsOf the 160 participants who took part in the survey, 17 reported occupational exposure to HIV (prevalence 10.6%, 95% CI 6.7-16.6), and of the 17 exposed, 10(58.8%) reported needlestick injuries. From those who were exposed, only 10 (58.8%) reported the incidents and went on post-exposure prophylaxis. However, only 6 out of the 10 completed their treatment. Half (50%) of the participants had inadequate knowledge on HIV post-exposure prophylaxis, 83.3% had adequate attitudes towards HIV post-exposure prophylaxis and 75% had adequate infection control practices.
conclusionOne out of every nine nurses had occupational exposure to HIV at a major tertiary hospital with poor reporting and utilization of post-exposure prophylaxis. The high proportion of needle stick injuries highlights the need for better infection control training. Similarly, the low levels of HIV post-exposure prophylaxis knowledge show the need for structured intervention and in-service training for health care workers.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.