ArticleAIDS (London, England)2020
Psychiatric trajectories across adolescence in perinatally HIV-exposed youth: the role of HIV infection and associations with viral load.
Article in AIDS (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- Cognitive Functioning and Its Stability Among Young Adults with Perinatal HIV Exposure or Acquisition in a U.S.-Based Longitudinal Cohort Study.AIDS and behavior · 2026Article
- Place Security and Mental Health: Two Sides of the Same Coin Among Young Adults with Perinatally-Acquired HIV and Exposure in New York City.AIDS and behavior · 2026Article
- Longitudinal trajectories of depressive symptoms in children are associated with baseline inflammation and HIV status.Communications health · 2026Article
- Longitudinal trajectories of depressive symptoms in children are influenced by baseline inflammation and HIV status.medRxiv : the preprint server for health sciences · 2025Article
- Qualitative evaluation of the multilevel influences on mental health and barriers and facilitators to care among Mozambican adolescents with HIV.SSM. Mental health · 2025Article
- Optimizing generalized anxiety disorder screening in young adults perinatally affected by HIV: A psychometric analysis.Journal of mood and anxiety disorders · 2024Article
- "We did more than survive": lessons learned from studies of risk and resilience of young people growing up with HIV and mental health needs.AIDS care · 2024Article
- Hope for the future protects against suicidal ideation among adolescents and young adults affected by perinatal HIV.AIDS care · 2023Article
- Condomless Sex Among HIV-affected AYA in an Era of Undetectable = Untransmittable and Pre-exposure Prophylaxis.AIDS and behavior · 2023Article
- Article
- Screening for depression with the PHQ-9 in young adults affected by HIV.Journal of affective disorders · 2022Article
- Navigating Stigma Trajectory and Mental Health Among Young Adults Living with Perinatal HIV in New York City.AIDS and behavior · 2021Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveIdentify factors associated with trajectories of psychiatric disorder among 340 adolescents and young adults (AYA) living with perinatal HIV infection (PHIV) and perinatal HIV-exposure but not infection (PHEU).
designLongitudinal cohort study of AYA in New York City, 9-16 years at enrollment.
methodsWe used multivariate longitudinal latent class analysis to identify trajectories of psychiatric disorder, and logistic regression to examine predictors of trajectories (e.g. PHIV status) and associations between trajectories and viremia in young adulthood (AYA with PHIV only).
resultsAmong all AYA, we identified three psychiatric trajectories: relatively 'low disorder' (63%), 'consistent anxiety' (26%), and 'escalating comorbidity' (11%). Compared with AYA with 'low disorder', AYA with 'escalating comorbidity' were significantly older, reported more neighborhood stress, and lived with a caregiver with alcohol use disorder, whereas AYA with 'consistent anxiety' were more likely female individuals. Although we found no statistically significant HIV status differences, among AYA with PHIV, nearly half (48%) were viremic in young adulthood, with higher odds of viremia among AYA with 'escalating comorbidity' (OR: 3.88, 95% CI: 0.93-16.26) and 'consistent anxiety' (OR: 2.41, 95% CI: 1.011-5.75) compared with 'low disorder'.
conclusionDespite significant adversity, AYA with PHIV and PHEU had relatively low prevalence of psychiatric disorder over time, although one-third had consistent or escalating psychiatric disorders. Among AYA with PHIV, psychiatric trajectories were associated with viremia in young adulthood. Given the growing population of AYA living with PHIV and PHEU worldwide, addressing the substantial and evolving mental health needs of both groups as they reach young adulthood is critical.
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