ArticleAIDS (London, England)2020
Clinic-level and individual-level factors that influence HIV viral suppression in adolescents and young adults: a national survey in Kenya.
Article in AIDS (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Characterizing the HIV care continuum among children and adolescents with HIV in eastern and southern Africa in the era of "Universal Test and Treat": A systematic review and meta-analysis.Journal of the International AIDS Society · 2025Pooled it
- Transition to independent care for youth living with HIV: a cluster randomised clinical trial.The lancet. HIV · 2022Trial
- Risk factors for HIV virological non-suppression among adolescents with common mental disorder symptoms in Zimbabwe: a cross-sectional study.Journal of the International AIDS Society · 2021Trial
- "Journal of the International Association of Providers of AIDS CareTrial
- Factors associated with viral suppression and antiretroviral therapy adherence among adolescents and young adults living with HIV in the African Cohort Study.Journal of acquired immune deficiency syndromes (1999) · 2026Article
- HIV viral load suppression and associated factors among PLHIV with non-communicable diseases in Uganda's Teso Region: a cross-sectional retrospective study.AIDS research and therapy · 2026Article
- Factors Associated With Viral Load Suppression Among Adolescents and Young Adults Living With HIV on ART in Rwanda: Data From Rwanda HIV Case-Based Surveillance, 2019-2025.Journal of tropical medicine · 2026Article
- Prevalence and Determinants of Viral Suppression in Young People Living with HIV on Antiretroviral Therapy in Southern Africa: A Cross-Sectional Analysis of HIV Survey Data of 2020 and 2021.AIDS and behavior · 2025Article
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- Development of machine learning algorithms to predict viral load suppression among HIV patients in Conakry (Guinea).Frontiers in artificial intelligence · 2025Article
- Article
- An Integrated Sample Referral System for HIV Viral Load and Early Infant Diagnosis in North-Western Province, Zambia-A Retrospective Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2024Article
- Temporal dynamics and drivers of durable HIV viral load suppression and persistent high- and low-level viraemia during Universal Test and Treat scale-up in Uganda: a population-based study.Journal of the International AIDS Society · 2024Article
- Trend and factors associated with non-suppression of viral load among adolescents on ART in Tanzania: 2018-2021.Frontiers in reproductive health · 2024Article
- Effect of Multi-Month Dispensing on Viral Suppression for Newly Enrolled Adolescents and Adults in Northern Nigeria.HIV/AIDS (Auckland, N.Z.) · 2023Article
- Simulated patient training to improve youth engagement in HIV care in Kenya: A stepped wedge cluster randomized controlled trial.PLOS global public health · 2023Article
- Using the RE-AIM framework to evaluate the implementation of scaling-up the Friendship Bench in Zimbabwe - a quantitative observational study.BMC health services research · 2022Observational
- Prevalence and Correlates of Viral Load Suppression and Human Immunodeficiency Virus (HIV) Drug Resistance Among Children and Adolescents in South Rift Valley and Kisumu, Kenya.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
- Improving viral load utilisation to enhance care for Kenyan adolescents with HIV.BMJ open quality · 2022Article
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15 authors.
Funding
Abstract
objectivesTo determine clinic-level and individual-level correlates of viral suppression among HIV-positive adolescents and young adult (AYA) aged 10-24 years receiving antiretroviral treatment (ART).
designMultilevel cross-sectional analysis using viral load data and facility surveys from HIV treatment programs throughout Kenya.
methodsWe abstracted medical records of AYA in HIV care, analyzed the subset on ART for more than 6 months between January 2016 and December 2017, and collected information on services at each clinic. Multilevel logistic regression models were used to determine correlates of viral suppression at most recent assessment.
resultsIn 99 HIV clinics, among 10 096 AYA on ART more than 6 months, 2683 (27%) had unsuppressed viral load at last test. Among 16% of clinics, more than 80% of AYA were virally suppressed. Clinic-level correlates of individual viral suppression included designated adolescent spaces [aOR: 1.32, 95% CI (1.07-1.63)] and faster viral load turnaround time [aOR: 1.06 (95% CI 1.03-1.09)]. Adjusting for clinic-level factors, AYA aged 10-14 and 15-19 years had lower odds of viral suppression compared with AYA aged 20-24 years [aOR: 0.61 (0.54-0.69) and 0.59 (0.52-0.67], respectively. Compared with female patients, male patients had lower odds of viral suppression [aOR: 0.69 (0.62-0.77)]. Compared with ART duration of 6-12 months, ART for 2-5, above 5-10 or more than 10 years was associated with poor viral suppression (P < 0.001).
conclusionDedicated adolescent space, rapid viral load turnaround time, and tailored approaches for male individuals and perinatally infected AYA may improve viral suppression. Routine summarization of viral load suppression in clinics could provide benchmarking to motivate innovations in clinic-AYA and individual-AYA care strategies.
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