Evidence map›Paper›PMID 32286627›Full record

ArticleNucleic acids research2020

rMAPS2: an update of the RNA map analysis and plotting server for alternative splicing regulation.

Jae Y Hwang, Sungbo Jung, Tae L Kook, Eric C Rouchka, Jinwoong Bok, Juw W Park

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 92 citations in OpenAlex.

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  15. Epitranscriptomic sculpting: the role of mMedical oncology (Northwood, London, England) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jae Y HwangDepartment of Computer Science and Engineering, University of Louisville, Louisville, KY 40292, USA.
Sungbo JungDepartment of Computer Science and Engineering, University of Louisville, Louisville, KY 40292, USA.
Tae L KookDepartment of Computer Science and Engineering, University of Louisville, Louisville, KY 40292, USA.
Eric C RouchkaDepartment of Computer Science and Engineering, University of Louisville, Louisville, KY 40292, USA.
Jinwoong BokDepartment of Anatomy, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Juw W ParkDepartment of Computer Science and Engineering, University of Louisville, Louisville, KY 40292, USA.
University of Louisville · USYonsei University · KR

Funding

WKU Lead Faculty AwardP20GM103436 · NIGMS · UNIVERSITY OF LOUISVILLE · PI ERIC C ROUCHKA · 2012 to 2026
$60.1M
Detecting and characterizing circular RNAs using high-throughput sequencing dataR15GM126446 · NIGMS · UNIVERSITY OF LOUISVILLE · PI PARK, JUW WON · 2017 to 2017
$462k
NIGMS NIH HHS P20 GM103436NIGMS NIH HHS R15 GM126446
6 · The paper itself

Abstract

The rMAPS2 (RNA Map Analysis and Plotting Server 2) web server, freely available at http://rmaps.cecsresearch.org/, has provided the high-throughput sequencing data research community with curated tools for the identification of RNA binding protein sites. rMAPS2 analyzes differential alternative splicing or CLIP peak data obtained from high-throughput sequencing data analysis tools like MISO, rMATS, Piranha, PIPE-CLIP and PARalyzer, and then, graphically displays enriched RNA-binding protein target sites. The initial release of rMAPS focused only on the most common alternative splicing event, skipped exon or exon skipping. However, there was a high demand for the analysis of other major types of alternative splicing events, especially for retained intron events since this is the most common type of alternative splicing in plants, such as Arabidopsis thaliana. Here, we expanded the implementation of rMAPS2 to facilitate analyses for all five major types of alternative splicing events: skipped exon, mutually exclusive exons, alternative 5' splice site, alternative 3' splice site and retained intron. In addition, by employing multi-threading, rMAPS2 has vastly improved the user experience with significant reductions in running time, ∼3.5 min for the analysis of all five major alternative splicing types at once.

Indexed as

Alternative SplicingSoftwareAnimalsArabidopsisBinding SitesCattleExonsHumansIntronsMiceNucleotide MotifsRatsRNARNA-Binding ProteinsRNA Splice SitesSequence Analysis, RNARNARNA-Binding ProteinsRNA Splice Sites

Identifiers

PMID32286627
PMCPMC7319468
OpenAlexW3016230169

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.